ArticleCartilage
Loading during Midstance of Gait Is Associated with Magnetic Resonance Imaging of Cartilage Composition Following Anterior Cruciate Ligament Reconstruction.
Article in Cartilage. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 29 citations in OpenAlex.
- Peak Vertical Ground Reaction Force Modifies Gait Biomechanics Bilaterally Following ACL Reconstruction: A Randomized Experiment.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Trial
- Modifying loading during gait leads to biochemical changes in serum cartilage oligomeric matrix protein concentrations in a subgroup of individuals with anterior cruciate ligament reconstruction.Clinical rheumatology · 2024Trial
- Human synovial fluid interleukin-6, but not type II collagen breakdown, positively correlated with pain after anterior cruciate ligament injury and reconstruction.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023Trial
- Increasing dynamic limb-level loading via real-time biofeedback decreases cumulative loading impulse during gait post-anterior cruciate ligament reconstruction.Clinical biomechanics (Bristol, Avon) · 2026Article
- Effects of Quadriceps Strength Recovery in the First Year After Anterior Cruciate Ligament Reconstruction on Gait Biomechanics.Sports health · 2026Article
- Personalized musculoskeletal models show that gait biofeedback alters knee cartilage contact mechanics in ACL-reconstructed subjects.Journal of biomechanics · 2026Article
- Gait Biomechanical Profiles Following Anterior Cruciate Ligament Reconstruction in Sexually-Immature Pediatrics.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026Article
- Associations between habitual walking speed and in vivo tibial cartilage strain in individuals with anterior cruciate ligament reconstruction.Osteoarthritis imaging · 2026Article
- Tibiofemoral Joint Contact Force Profiles of Pediatric Patients After Anterior Cruciate Ligament Reconstruction.The American journal of sports medicine · 2025Article
- Influence of Running Speed and Time Postoperatively on Lower Extremity Work in Collegiate Athletes after Anterior Cruciate Ligament Reconstruction.Medicine and science in sports and exercise · 2025Article
- Aberrant Gait Biomechanics Linked to Cartilage Changes After ACL Reconstruction in Those With High Body Mass Index.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Lower Extremity Mechanical Energetics During Walking 6 Months Following Anterior Cruciate Ligament Reconstruction.Scandinavian journal of medicine & science in sports · 2025Article
- Biomechanical Threshold Values for Identifying Clinically Significant Knee-Related Symptoms 6 Months After Anterior Cruciate Ligament Reconstruction.Journal of athletic training · 2025Article
- Investigating the Impact of Preoperative Kinesiophobia and Pain on Postoperative Gait Biomechanics Following Anterior Cruciate Ligament Injury.Orthopaedic journal of sports medicine · 2025Article
- Early Gait Biomechanics Linked to Daily Steps After Anterior Cruciate Ligament Reconstruction.Journal of athletic training · 2025Article
- Bilateral waveform analysis of gait biomechanics presurgery to 12 months following ACL reconstruction compared to controls.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Walking gait biomechanics in individuals with quadriceps tendon autograft anterior cruciate ligament reconstruction.Frontiers in sports and active living · 2025Article
- Evaluating Gait with Force Sensing Insoles 6 Months after Anterior Cruciate Ligament Reconstruction: An Autograft Comparison.Medicine and science in sports and exercise · 2025Article
- Peak vertical ground reaction force used to identify sub-groups of individuals with differing biomechanical gait profiles post-anterior cruciate ligament reconstruction.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024Article
- Sustained Limb-Level Loading: A Ground Reaction Force Phenotype Common to Individuals at High Risk for and Those With Knee Osteoarthritis.Arthritis & rheumatology (Hoboken, N.J.) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
objectiveA complex association exists between aberrant gait biomechanics and posttraumatic knee osteoarthritis (PTOA) development. Previous research has primarily focused on the link between peak loading during the loading phase of stance and joint tissue changes following anterior cruciate ligament reconstruction (ACLR). However, the associations between loading and cartilage composition at other portions of stance, including midstance and late stance, is unclear. The objective of this study was to explore associations between vertical ground reaction force (vGRF) at each 1% increment of stance phase and tibiofemoral articular cartilage magnetic resonance imaging (MRI) T1ρ relaxation times following ACLR.
designTwenty-three individuals (47.82% female, 22.1 ±4.1 years old) with unilateral ACLR participated in a gait assessment and T1ρ MRI collection at 12.25 ± 0.61 months post-ACLR. T1ρ relaxation times were calculated for the articular cartilage of the weightbearing medial and lateral femoral (MFC, LFC) and tibial (MTC, LTC) condyles. Separate bivariate, Pearson product moment correlation coefficients (
resultsGreater vGRF during midstance (46%-56% of stance phase) was associated with greater T1ρ MRI relaxation times in the MFC (
conclusionsBiomechanical gait profiles that include greater vGRF during midstance are associated with MRI estimates of lesser proteoglycan density in the MFC. Inability to unload the ACLR limb during midstance may be linked to joint tissue changes associated with PTOA development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.