SynthesisJournal of clinical pharmacy and therapeutics2022
Systematic review of the prevalence and nature of drug-related problems in paediatric patients.
Synthesis in Journal of clinical pharmacy and therapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The epidemiology of drug-related hospital admissions in paediatrics - a systematic review.Archives of public health = Archives belges de sante publique · 2024Pooled it
- Systematic review of the prevalence and nature of drug-related problems in paediatric patients.Journal of clinical pharmacy and therapeutics · 2022Pooled it
- Drug-related problems in pediatric patients with chronic kidney disease: A single-center prospective study.Experimental and therapeutic medicine · 2026Article
- Drug-related problems and their predictors in pediatric community-acquired infections: the role of pharmacist-led interventions in Pakistan.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2026Article
- Effectiveness of a Structured Pharmacist-led Intervention in Improving Pediatric Outpatient Prescribing Quality in a Resource-limited Setting: A Pre-post Study.Journal of research in pharmacy practice · 2026Article
- Assessment of non-steroidal anti-inflammatory drugs use and its complications among pediatric patients at a private tertiary care hospital in Malaysia.BMC pediatrics · 2025Article
- Drug-related problems among pediatric intensive care units: prevalence, risk factors, and clinical pharmacists' interventions.BMC pediatrics · 2024Article
- Effect of Pharmacist-Led Interventions on Physicians' Prescribing for Pediatric Outpatients.Healthcare (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
WHAT IS KNOWN AND
objectiveA drug-related problem (DRP) is "an event or circumstance involving drug therapy that actually or potentially interferes with the desired health outcome." The paediatric population is easily affected by DRPs. The aim of this study was to evaluate different types and characteristics of DRPs in paediatric patients. This finding can be used as a baseline in epidemiology for assessing potential risk factors for DRPs in paediatric patients.
methodsAn extensive search strategy was designed to retrieve all articles published from the date of inception of the database to 1 May 2020, by combining the terms "drug-related problem" and "paediatric" in several electronic databases (PubMed, Cochrane Library, Embase and Web of Science) and following the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. Observational and interventional studies report that the epidemiology of DRPs in paediatric patients was included. Two reviewers independently screened studies, extracted data, assessed the quality of the included studies and then qualitatively analysed the results.
resultsEighteen studies were included in the final analysis, and 6 different classification systems on paediatric-related DRPs were reported. Overall, these studies showed that paediatric patients are easily affected by DRPs. However, the majority of DRPs are considered preventable, and the severity of DRPs in paediatric patients is mostly considered minor and moderate. Dosing-related problems rank highest in terms of frequency, and the number of prescribed drugs has a positive correlation with the occurrence of DRPs. WHAT IS NEW AND
conclusionThis study showed that paediatric patients are easily affected by DRPs, but the majority of DRPs are preventable, which indicate that actions should be taken. To reduce DRPs in paediatric patients of the interventions that are noticed, clinical pharmacy services show promising improvement on reducing DRPs compared with other interventions.
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