Evidence map›Paper›PMID 35098483›Full record

ReviewMolecular biotechnology2022

Long Non-coding RNA ZFPM2-AS1: A Novel Biomarker in the Pathogenesis of Human Cancers.

Gabriel B K Sasa, Cheng Xuan, Guoliang Lyu, Xianfeng Ding, Fang Meiyu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabriel B K SasaCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, 310018, Hangzhou, People's Republic of China.
Cheng XuanCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, 310018, Hangzhou, People's Republic of China.
Guoliang LyuZhejiang Sci-Tech University Library, Hangzhou, 310018, People's Republic of China.
Xianfeng DingCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, 310018, Hangzhou, People's Republic of China.
Fang MeiyuDepartment of Rare and Head and Neck Oncology, Key Laboratory of Head and Neck Cancer, Translational Research of Zhejiang Province, Hangzhou, People's Republic of China. fangmy@zjcc.org.cn.ORCID http://orcid.org/0000-0001-9369-3640

Funding

Foundation of Science technology Department of Zhejiang Province LGF21C050001
6 · The paper itself

Abstract

Due to their biological activities in regulating dosage compensation, epigenetics, and cell differentiation, long non-coding RNAs (lncRNA) have been recognized as important regulators of the beginning and development of human malignancies. LncRNA dysregulation has a significant impact on a range of cellular functions, including proliferation, migration, invasion, and anti-apoptosis activity. Recently, aberrant expression of the long non-coding RNA zinc finger protein multitype 2 antisense RNA 1 (ZFPM2-AS1) was observed in a range of solid tumors and correlated significantly with tumor size, histological differentiation, lymph node metastasis, malignant tumor (TNM) stage, short survival, and prognosis. Additional mechanical analysis indicated that ZFPM2-AS1 was involved in several cellular activities, including proliferation, migration, invasion, cell cycle progression, and apoptosis, through microRNAs (miRNAs), signaling pathways, and other biological components or proteins. This review summarizes the current status of research on ZFPM2-AS1 in various human malignancies and discusses its mechanism of action and clinical significance in tumor development and progression.

Indexed as

MicroRNAsNeoplasmsRNA, Long NoncodingBiomarkersCell Line, TumorCell MovementCell ProliferationDNA-Binding ProteinsGene Expression Regulation, NeoplasticHumansRNA, AntisenseTranscription FactorsBiomarkersDNA-Binding ProteinsMicroRNAsRNA, AntisenseRNA, Long NoncodingTranscription FactorsZFPM2 protein, humanBiomarkerCancerlncRNAsPathogenesisZFPM2-AS1

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.