Evidence map›Paper›PMID 35098425›Full record

ReviewCurrent neurology and neuroscience reports2022

Endovascular Treatment of Acute Stroke.

James A Giles, Ananth K Vellimana, Opeolu M Adeoye

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current neurology and neuroscience reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

James A GilesDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-3197-3062
Ananth K VellimanaDepartments of Neurosurgery, Neurology and Radiology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0003-2056-6610
Opeolu M AdeoyeDepartment of Emergency Medicine, Washington University School of Medicine, St. Louis, MO, USA. adeoye@wustl.edu.ORCID 0000-0001-8666-5369

Funding

Multi-arm Optimization of Stroke Thrombolysis (MOST) Stroke TrialU01NS100699 · NINDS · WASHINGTON UNIVERSITY · PI ADEOYE, OPEOLU M, BARRETO, ANDREW D · 2018 to 2021
$18.8M
Strategies to Innovate EmeRgENcy Care Clinical Trials Network ("SIREN") - SupplementU24NS100688 · NINDS · UNIVERSITY OF CINCINNATI · PI FERMANN, GREGORY J., MCMULLAN, JASON · 2017 to 2022
$922k
American Heart Association 827728NINDS NIH HHS U01 NS100699NINDS NIH HHS U24 NS100688
6 · The paper itself

Abstract

purpose of reviewIn the USA, around 30% of 795,000 strokes per year are due to proximal large-vessel occlusion, and these are a major cause of death and disability. We review the most recent advances regarding treatment of ischemic stroke amenable to mechanical thrombectomy. RECENT

findingsIn the last four years, clinical trial evidence has expanded the time window for successful endovascular treatment to 24 h. Current research is aimed at expanding patient selection to mild strokes, large ischemic cores and occlusions of smaller, more distal blood vessels. Further, we have developed understanding of how to manage blood pressure after thrombectomy and even had promising results for a neuroprotective agent in these patients. Thrombectomy has transformed the treatment of ischemic stroke due to large-vessel occlusion. Recent research has focused on expanding patient candidacy for endovascular treatment and improving medical management to support better neurologic outcomes.

Indexed as

Endovascular ProceduresIschemic StrokeThrombectomyHumansLarge-vessel occlusionStrokeThrombectomy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.