Evidence map›Paper›PMID 35098261›Full record

ArticleJournal of pediatrics & child health care2021

Early Childhood Caries Experience Associated with Upper Respiratory Infection in US Children: Findings from a Retrospective Cohort Study.

A Albelali, T T Wu, H Malmstrom, J Xiao

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pediatrics & child health care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

A AlbelaliEastman Institute for Oral Health, University of Rochester, Medical Center, Rochester, NY, USA.
T T WuBiostatistics and Computational Biology, University of Rochester, Medical Center, Rochester, NY, USA.
H MalmstromEastman Institute for Oral Health, University of Rochester, Medical Center, Rochester, NY, USA.
J XiaoEastman Institute for Oral Health, University of Rochester, Medical Center, Rochester, NY, USA.
University of Rochester Medical Center · US

Funding

Association between Oral Candida albicans and the Onset of Severe Early Childhood CariesK23DE027412 · NIDCR · UNIVERSITY OF ROCHESTER · PI XIAO, JIN · 2018 to 2022
$748k
NIDCR NIH HHS K23 DE027412
6 · The paper itself

Abstract

introductionBoth Early Childhood Caries (ECC) and Upper Respiratory Infection (URI) are infectious diseases. The oral cavity is considered a potential reservoir of respiratory pathogens due to the anatomical proximity between the oral cavity and respiratory system, which implies a potential association between ECC and URI. Hence, this study aimed to evaluate the association between ECC experience and URI incidence in preschool children.

methodsThis retrospective cohort study collected data

resultsA total of 497 US preschool children were included, with 117 ECC and 380 CF children. More children with ECC (58.1%) developed URI than the CF group (47.6%) during the follow-up period (4-6 years of age) (p=0.04). The ECC children were at 1.6 times higher risk to develop URI than the CF children even after accounting for other URI risk factors (Hazard Ratio 1.57 (1.13, 2.10), p=0.007).

conclusionsOur study suggests a potential association between ECC and URI, with an inference that early life ECC experience could be used as a predictor for developing URI in preschool age. The causal relationship between ECC and URI incidence in young children needs to be investigated through future studies.

Indexed as

ChildrenDental CariesEarly childhood cariesPediatric healthUpper respiratory infection

Identifiers

PMID35098261
PMCPMC8796997
OpenAlexW3206372979

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.