Evidence map›Paper›PMID 35098142›Full record

ArticleEndocrinology and disorders : open access2021

Maternal 3,3'-Diiodothyronine Sulfate Formation from Guinea Pig Placenta Perfused with 3,3',5-Triodothyronine.

Sing-Yung Wu, Charles H Emerson, Edward Tjioe, Dong-Bao Chen

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Endocrinology and disorders : open access, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sing-Yung WuDepartment of Radiology and Research, Veteran Administration University of California Irvine Medical Center, Long Beach, CA 90822.
Charles H EmersonDepartment of Medicine, University of Massachusetts Medical School, Worcester, MA 01605.
Edward TjioeDepartment of Physiology and Anatomy, California State University of Long Beach, CA 90803.
Dong-Bao ChenDepartment of Obstetrics and Gynecology, University of California Irvine, Irvine, CA 92697.
University of Massachusetts Chan Medical School · US

Funding

Actions of Estrogen on Uterine Artery EndotheliumR01HL070562 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHEN, DONGBAO · 2001 to 2025
$6.3M
Pregnancy-Dependent Protein Sulfyhydration in Human Uterine ArteryR21HD097498 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, DONGBAO · 2019 to 2020
$425k
NHLBI NIH HHS R01 HL070562NICHD NIH HHS R21 HD097498
6 · The paper itself

Abstract

objectiveSerum 3, 3',5-triiodothyronine (T MATERIALS AND

methodsOne-pass placenta perfusions performed on pregnant guinea pigs were studied between 58 - 65 days of gestation. In two separate experiments, the umbilical artery of the guinea pig placenta was perfused in situ at 37°C with outer-ring labeled [

resultsSulfated [

conclusionsThe expression of type 3 deiodinase (D3) and thyroid hormone sulfotransferase activity in placenta may play an important role to protect developing organs against undue exposure to active thyroid hormone in late gestation in the fetus. The combined activities of D3 and sulfotransferase promoted a placental transfer of T

Indexed as

placental functionplacental transfersulfation of thyroid hormonethyroid hormones

Identifiers

PMID35098142
PMCPMC8797160
OpenAlexW4200165399

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.