Evidence map›Paper›PMID 35098004›Full record

ArticleCurrent developments in nutrition2022

TRB3 Deletion Has a Limited Effect on Milk Fat Synthesis and Milk Fat Depression in C57BL/6N Mice.

Rachel E Walker, Liying Ma, Chengmin Li, Yun Ying, Kevin J Harvatine

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current developments in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rachel E WalkerDepartment of Nutritional Sciences, The Pennsylvania State University, University Park, PA, USA.ORCID https://orcid.org/0000-0002-8845-858X
Liying MaDepartment of Animal Sciences, The Pennsylvania State University, University Park, PA, USA.
Chengmin LiDepartment of Animal Sciences, The Pennsylvania State University, University Park, PA, USA.
Yun YingDepartment of Animal Sciences, The Pennsylvania State University, University Park, PA, USA.
Kevin J HarvatineDepartment of Animal Sciences, The Pennsylvania State University, University Park, PA, USA.
Pennsylvania State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRegulation of the endoplasmic reticulum (ER) stress pathway is critical to mammary epithelial cell function throughout pregnancy, lactation, and involution. Treatment with

objectivesOur objective was to describe the effect of TRB3 deficiency on milk fat synthesis and determine if TRB3 deficiency protects against suppression of mammary lipogenesis.

methodsFirst, mammary

results

conclusionsOverall, TRB3 plays a minor role in regulating mammary lipogenesis, because

Indexed as

cis-12 conjugated linoleic acidendoplasmic reticulum stressmilk fat depressionmilk fat synthesistrans-10tribbles pseudokinase 3

Identifiers

PMID35098004
PMCPMC8791759
OpenAlexW4210267744

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.