Evidence map›Paper›PMID 35097327›Full record

ReviewFoot & ankle orthopaedics2019

The Use of Bone Grafts, Bone Graft Substitutes, and Orthobiologics for Osseous Healing in Foot and Ankle Surgery.

Jonathan R Peterson, Fangyu Chen, Eugene Nwankwo, Travis J Dekker, Samuel B Adams

Open access · goldAbstract readReview
In one paragraph

Review in Foot & ankle orthopaedics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Comparative Studies of Bone Graft and Orthobiologics for Foot Ankle Arthrodesis: A Critical Review.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2024
    Review
  5. Management of non-unions of the malleolar fractures- Current Evidence.Journal of clinical orthopaedics and trauma · 2024
    Article
  6. Review
  7. A Mouse Femoral Ostectomy Model to Assess Bone Graft Substitutes.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jonathan R PetersonDepartment of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA.ORCID https://orcid.org/0000-0003-4534-7334
Fangyu ChenDepartment of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA.
Eugene NwankwoDepartment of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA.
Travis J DekkerDepartment of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA.
Samuel B AdamsDepartment of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA.
Duke Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Achieving fusion in osseous procedures about the foot and ankle presents unique challenges to the surgeon. Many patients have comorbidities that reduce osseous healing rates, and the limited space and high weightbearing demand placed on fusion sites makes the choice of bone graft, bone graft substitute, or orthobiologic agent of utmost importance. In this review, we discuss the essential characteristics of grafts, including their osteoconductive, osteoinductive, osteogenic, and angiogenic properties. Autologous bone graft remains the gold standard and contains all these properties. However, the convenience and lack of donor site morbidity of synthetic bone grafts, allografts, and orthobiologics, including growth factors and allogenic stem cells, has led to these being used commonly as augments. LEVEL OF EVIDENCE: Level V, expert opinion.

Indexed as

allograftautograftBMPbone marrow aspirateorthobiologicsPDGFstem cells

Identifiers

PMID35097327
PMCPMC8500392
OpenAlexW2961786432

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.