ArticleFrontiers in veterinary science2021
Genetic Diversity in the Italian Holstein Dairy Cattle Based on Pedigree and SNP Data Prior and After Genomic Selection.
Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 52 citations in OpenAlex.
- The mitogenome diversity of Alpine Rendena cattle: new clues on its maternal origin and the complex substructure of haplogroup T3.Genetics, selection, evolution : GSE · 2026Article
- Mucopolysaccharidosis IIID and Beta-Mannosidosis in Brazilian Anglo-Nubian Goats: Molecular and Genealogical Insights for the Development and Implementation of a Genetic Disease Eradication Program.Animal genetics · 2026Article
- Genetic Diversity and Population Structure of Sardo Negro Cattle.Animals : an open access journal from MDPI · 2026Article
- Runs of homozygosity in Italian Holstein bulls: a permutation approach and time-based mapping of the genomic regions potentially under selection.BMC genomics · 2026Article
- Ripening-Associated Changes in Fatty Acid Composition and Nutritional Indices in Caciocavallo Silano PDO Cheese.Foods (Basel, Switzerland) · 2025Article
- Genomic diversity and population structure analysis of four geographically distinct Holstein cattle populations using genome-wide DNA profiling.Archives animal breeding · 2025Article
- Ecuadorian Holstein-Friesian cattle paternal lineages: Demographic structure, inbreeding evolution, and genetic diversity.PloS one · 2025Article
- Analyses of whole-genome sequences from 185 North American Thoroughbred horses, spanning 5 generations.Scientific reports · 2024Article
- Adipose gene expression profiles in Northern Finncattle, Mirandesa cattle, Yakutian cattle and commercial Holstein cattle.Scientific reports · 2024Article
- Genomic diversity and population structure of Carniolan honey bee in its native habitat.BMC genomics · 2024Article
- Article
- Genomic prediction and genome-wide association study using combined genotypic data from different genotyping systems: application to apple fruit quality traits.Horticulture research · 2024Article
- Genetic Variation and Composition of Two Commercial Estonian Dairy Cattle Breeds Assessed by SNP Data.Animals : an open access journal from MDPI · 2024Article
- Single-Step Genomic Prediction of Superovulatory Response Traits in Japanese Black Donor Cows.Biology · 2023Article
- Article
- Herd Level Yield Gap Analysis in a Local Scale Dairy Farming System: A Practical Approach to Discriminate between Nutritional and Other Constraining Factors.Animals : an open access journal from MDPI · 2023Article
- The role of inbreeding depression on productive performance in the Italian Holstein breed.Journal of animal science · 2023Article
- Pedigree and genome-based patterns of homozygosity in the South African Ayrshire, Holstein, and Jersey breeds.Frontiers in genetics · 2023Article
- Genomic inbreeding coefficients using imputed genotypes: assessing differences among SNP panels in Holstein-Friesian dairy cows.Frontiers in veterinary science · 2023Article
- Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetic diversity has become an urgent matter not only in small local breeds but also in more specialized ones. While the use of genomic data in livestock breeding programs increased genetic gain, there is increasing evidence that this benefit may be counterbalanced by the potential loss of genetic variability. Thus, in this study, we aimed to investigate the genetic diversity in the Italian Holstein dairy cattle using pedigree and genomic data from cows born between 2002 and 2020. We estimated variation in inbreeding, effective population size, and generation interval and compared those aspects prior to and after the introduction of genomic selection in the breed. The dataset contained 84,443 single-nucleotide polymorphisms (SNPs), and 74,485 cows were analyzed. Pedigree depth based on complete generation equivalent was equal to 10.67. A run of homozygosity (ROH) analysis was adopted to estimate SNP-based inbreeding (F
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