Evidence map›Paper›PMID 35097025›Full record

ArticleFrontiers in cardiovascular medicine2021

Genetic Determinants of Serum Calcification Propensity and Cardiovascular Outcomes in the General Population.

Amber de Haan, Fariba Ahmadizar, Peter J van der Most, Chris H L Thio, Zoha Kamali, Alireza Ani, Mohsen Ghanbari, Layal Chaker, Joyce van Meurs, M Kamran Ikram and 8 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 3 countries.

Amber de HaanDivision of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Fariba AhmadizarDepartment of Epidemiology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, Netherlands.
Peter J van der MostDepartment of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Chris H L ThioDepartment of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Zoha KamaliDepartment of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Alireza AniDepartment of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Mohsen GhanbariDepartment of Epidemiology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, Netherlands.
Layal ChakerDepartment of Epidemiology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, Netherlands.
Joyce van MeursDepartment of Internal Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, Netherlands.
M Kamran IkramDepartment of Epidemiology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, Netherlands.
Harry van GoorDepartment of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Stephan J L BakkerDivision of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Pim van der HarstDepartment of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.
Harold SniederDepartment of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Maryam KavousiDepartment of Epidemiology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, Netherlands.
Andreas PaschCalciscon AG, Biel, Switzerland.
Mark EijgelsheimDivision of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Martin H de BorstDivision of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Erasmus MC · NLUniversity Medical Center Groningen · NLUniversity of Groningen · NLUniversity Medical Center Utrecht · NLJohannes Kepler University of Linz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSerum calciprotein particle maturation time (T

methodsWe performed a genome-wide association study of serum T

resultsWe identified three independent genome-wide significant single nucleotide polymorphism (SNPs) in the

conclusionsWe identified three SNPs in the

Indexed as

AHSGcalcification propensitycardiovascular diseasefetuin-AGWASpopulation geneticsserum T50

Identifiers

PMID35097025
PMCPMC8795369
OpenAlexW4205967188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.