ArticleFrontiers in cellular and infection microbiology2021
Microbial Communities in the Extraradicular and Intraradicular Infections Associated With Persistent Apical Periodontitis.
Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- [Selection of indications for apical microsurgery in different types of affected teeth].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026Review
- Microbiome of Apical Intracanal and Extraradicular Biofilms From the Same Roots of Teeth With Persistent Apical Periodontitis: An Observational Study.International endodontic journal · 2026Observational
- Nell-1 inhibits osteoclast differentiation and bone resorption in apical periodontitis.Journal of molecular histology · 2026Article
- Immunomodulatory Role of Milk on Gut Microbiota: Implications for Enhancing Oral Vaccine Efficacy.Probiotics and antimicrobial proteins · 2026Review
- Is apical periodontitis a matter of microbial diversity or time? A scoping review.Head & face medicine · 2026Article
- Bioactive peptides in Endodontic infections: The Good, The Bad, and The Ugly.Probiotics and antimicrobial proteins · 2026Review
- [Microbial communities in extraradicular infections of post-treatment apical periodontitis without or with sinus tracts].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026Article
- A cross-sectional metagenomic analysis of the microbial ecology in symptomatic apical periodontitis - AnJournal of conservative dentistry and endodontics · 2026Article
- Exploring Relationships Within the Microbiome of Root Canal Infections and the Influence of Associated Clinical Parameters.International endodontic journal · 2025Article
- Clinical and radiographic success of lesion sterilization and tissue repair in primary teeth: a systematic review and meta-analysis.The Saudi dental journal · 2025Article
- A Retrospective Study of CBCT-Based Detection of Endodontic Failures and Periapical Lesions in a Romanian Cohort.Journal of clinical medicine · 2025Article
- In situ imaging and microbiome analysis of calculus-like deposits at the root apex: A case report of refractory apical periodontitis.International endodontic journal · 2025Article
- Impact of Different Nickel-titanium Instruments on Apical Micro-cracks Formation and Residual Amount of Root Canal Filling Materials Following Retreatment Procedure.European endodontic journal · 2025Article
- Influence of Diabetes on Periapical Pathology in Treated and Untreated Teeth: A Cross-Sectional Comparison with Non-Diabetic Patients.Journal of clinical medicine · 2025Article
- Extraradicular Infection and Apical Mineralized Biofilm: A Systematic Review of Published Case Reports.Journal of clinical medicine · 2025Review
- Apical periodontitis microbiome association with salivary and serum inflammatory burden.International endodontic journal · 2025Article
- Microbiome differences between trauma- and caries-derived periapical lesions using next-generation sequencing.Journal of oral microbiology · 2025Article
- Intestinal Microbiota Dysbiosis Disrupts the Mucosal Barrier, Triggering Inflammatory Responses in Gut-Kidney Interaction and Exacerbating Diarrhea.Journal of inflammation research · 2025Article
- Dental pathologies of endodontic origin and subsequent bacterial involvement - a literature review.Germs · 2023Review
- Nociceptor-Macrophage Interactions in Apical Periodontitis: How Biomolecules Link Inflammation with Pain.Biomolecules · 2023Review
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Authors and funding
4 authors.
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Abstract
Microorganisms in the complex root canal system and the extraradicular regions, including the periapical lesions and extraradicular biofilm may cause root canal treatment failures. However, few studies described the difference between the intraradicular and extraradicular infections from the same tooth associated with persistent apical periodontitis. This study aimed to characterize the microbiome present in the root canal, extraradicular biofilm, and periapical lesions associated with persistent apical periodontitis. The microbial communities in the root canal, extraradicular biofilm, and periapical lesions were investigated by Illumina high-throughput sequencing using Illumina Hiseq 2500 platform. The dominant phyla in the extraradicular and intraradicular infections associated with persistent apical periodontitis were
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