Evidence map›Paper›PMID 35096635›Full record

ArticleFrontiers in cellular and infection microbiology2021

Blood Biomarkers and Serologic Immunological Profiles Related to Periodontitis in Abdominal Aortic Aneurysm Patients.

Leila Salhi, Patrick Rijkschroeff, Dorien Van Hede, Marja L Laine, Wim Teughels, Natzi Sakalihasan, France Lambert

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Arteriosclerosis, thrombosis, and vascular biology · 2026
    Article
  3. Article
  4. Article
  5. International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Leila SalhiDepartment of Periodontology, Buccal Surgery and Implantology, Faculty of Medicine, Liège, Belgium.
Patrick RijkschroeffDepartment of Periodontology , Academic Centre for Dentistry Amsterdam, Vrije Universiteit (VU) Amsterdam, Amsterdam, Netherlands.
Dorien Van HedeDepartment of Periodontology, Buccal Surgery and Implantology, Faculty of Medicine, Liège, Belgium.
Marja L LaineDepartment of Periodontology , Academic Centre for Dentistry Amsterdam, Vrije Universiteit (VU) Amsterdam, Amsterdam, Netherlands.
Wim TeughelsDepartment of Oral Health Sciences, KU Leuven & Dentistry, University Hospitals Leuven, Leuven, Belgium.
Natzi SakalihasanDepartment of Cardiovascular and Thoracic Surgery, Faculty of Medicine, Liège, Belgium.
France LambertDepartment of Periodontology, Buccal Surgery and Implantology, Faculty of Medicine, Liège, Belgium.
Academic Center for Dentistry Amsterdam · NLKU Leuven · BEUniversity of Liège · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeriodontitis is a chronic inflammatory gum disease associated with systemic diseases such as cardiovascular diseases.

aimTo investigate the association of systemic blood biomarkers, C-reactive protein (CRP), levels of lipopolysaccharide (LPS), and IgG levels against periodontal pathogens

methodsPatients with stable AAA (n = 30) and unstable AAA (n = 31) were recruited. The anti-

resultsThe presence of antibodies against Pg and Aa, LPS and high CRP concentrations were found in all AAA patients. The IgG levels were similar in patients with stable and unstable AAA (both for Aa and Pg). Among investigated blood biomarkers, only CRP was associated with AAA stability. The amount of LPS in saliva, supra, and subgingival plaque were significantly associated with the systemic LPS (p <0.05).

conclusionsThis

Indexed as

Aortic Aneurysm, AbdominalPeriodontitisAggregatibacter actinomycetemcomitansBiomarkersHumansPorphyromonas gingivalisBiomarkersabdominal aortic aneurysm (AAA)inflammation and innate immunitymicrobiomeperiodontitisperiodontitis systemic interaction

Identifiers

PMID35096635
PMCPMC8798408
OpenAlexW4205320607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.