Evidence map›Paper›PMID 35096634›Full record

ArticleFrontiers in cellular and infection microbiology2021

Vaginal Dysbiotic Microbiome in Women With No Symptoms of Genital Infections.

Rinku Pramanick, Neelam Nathani, Himangi Warke, Niranjan Mayadeo, Clara Aranha

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 45 citations in OpenAlex.

  1. Trial
  2. Vaginal Microbiome and Preterm Birth in Pregnant Women From India.The journal of obstetrics and gynaecology research · 2026
    Article
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  10. Effect of intervention withJournal of clinical biochemistry and nutrition · 2025
    Article
  11. Article
  12. Microbiome impacts quality of life in patients with endometrial cancer and benign gynecological conditions.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  13. Article
  14. Article
  15. Hallmarks of Bacterial Vaginosis.Diagnostics (Basel, Switzerland) · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Rinku PramanickDepartment of Molecular Immunology and Microbiology, Indian Council of Medical Research (ICMR)-National Institute for Research in Reproductive and Child Health, Mumbai, India.
Neelam NathaniSchool of Applied Sciences & Technology (SAST-GTU), Gujarat Technological University, Ahmedabad, India.
Himangi WarkeDepartment of Obstetrics and Gynecology, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Mumbai, India.
Niranjan MayadeoDepartment of Obstetrics and Gynecology, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Mumbai, India.
Clara AranhaDepartment of Molecular Immunology and Microbiology, Indian Council of Medical Research (ICMR)-National Institute for Research in Reproductive and Child Health, Mumbai, India.
King Edward Memorial Hospital and Seth G.S. Medical College · INNational Institute for Research in Reproductive Health · INGujarat Technological University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vaginal microbiome plays a critical role in determining the progression of female genital tract infections; however, little is known about the vaginal microbiota of Indian women. We aimed to investigate the vaginal microbial architecture of women with asymptomatic bacterial vaginosis (BV) (n=20) and normal microbiota (n=19). Microbial diversity was analyzed in vaginal swabs from regularly menstruating women (18-45yrs) by 16S rRNA V3-V4 amplicon (MiSeq Illumina) sequencing. Rarefaction analysis showed a higher number of species in normal flora compared to BV. Alpha diversity as measured by Pielou's evenness revealed microbial diversity was significantly greater in BV samples than normal microbiota (p= 0.0165). Beta diversity comparison using UniFrac metrics indicated distinct microbial communities clustering between normal and BV flora. Firmicutes were the major phyla observed in vaginal specimens of normal microbiota whereas

Indexed as

DysbiosisMicrobiotaFemaleHumansProspective StudiesRNA, Ribosomal, 16SVaginaRNA, Ribosomal, 16Sasymptomatic BVbacterial vaginosis (BV)Lactobacillusmicrobiome & dysbiosisvaginal microbiota (VMB)

Identifiers

PMID35096634
PMCPMC8790106
OpenAlexW4210716192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.