Evidence map›Paper›PMID 35096320›Full record

ArticleArchives of Razi Institute2021

Identification of other Cellular Receptors for Edema Factor of

R Khandia, B Pattnaik, K Rajukumar, A K Pateriya, N Puranik, S Bhatia, H Murugkar

Open access · greenAbstract read
In one paragraph

Article in Archives of Razi Institute, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

R KhandiaICAR-National Institute for High Security Animal Diseases, Anand Nagar, Bhopal, MP, India.
B PattnaikProject Directorate on Foot and Mouth Disease, Indian Council of Agricultural Research, Mukteswar - Kumaon, Nainital, UK.
K RajukumarICAR-National Institute for High Security Animal Diseases, Anand Nagar, Bhopal, MP, India.
A K PateriyaICAR-National Institute for High Security Animal Diseases, Anand Nagar, Bhopal, MP, India.
N PuranikDepartment of Biochemistry and Genetics, Barkatullah University, Bhopal, MP, India.
S BhatiaICAR-National Institute for High Security Animal Diseases, Anand Nagar, Bhopal, MP, India.
H MurugkarICAR-National Institute for High Security Animal Diseases, Anand Nagar, Bhopal, MP, India.
National Institute of High Security Animal Diseases · INBarkatullah University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Edema factor (EF) is one of the major secretory proteins of anthrax bacteria along with protective antigen (PA) and lethal factor (LF). Edema factor is a calmodulin-and calcium-dependent adenylate cyclase that increases intracellular levels of cAMP. Intracellular trafficking of EF occurs through PA by binding to ATR/CMG2 receptors, which are also involved in other physiological functions of cells. cAMP is a secondary messenger which activates multiple signaling cascades involved in the cytokinetics of actin molecules and cell junction formation. The present study evaluated the effect of EF on growth and angiogenesis patterns in chicken embryos in the

Indexed as

Antigens, BacterialBacillus anthracisBacterial ToxinsReceptors, PeptideAdenylyl CyclasesAnimalsChick EmbryoVascular Endothelial Growth Factor AAdenylyl Cyclasesanthrax toxinanthrax toxin receptorsAntigens, BacterialBacterial ToxinsReceptors, PeptideVascular Endothelial Growth Factor AAngiogenesis inhibitionCAMcAMPEdema factorEmbryo growth retardationSignaling molecule

Identifiers

PMID35096320
PMCPMC8790966
OpenAlexW3200905241

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.