Evidence map›Paper›PMID 35096294›Full record

ArticleIranian journal of basic medical sciences2021

Preparation and evaluation of the exotoxin A nano-gold conjugate as a vaccine candidate for

Masoumeh Abbasi, Asghar Tanomand, Farshid Kafilzadeh, Samaneh Zolghadri, Hasan Hosainzadegan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of basic medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Masoumeh AbbasiDepartment of Microbiology, Jahrom Branch, Islamic Azad University, Jahrom, Iran.
Asghar TanomandDepartment of Microbiology, Maragheh University of Medical Sciences, Maragheh, Iran.
Farshid KafilzadehDepartment of Microbiology, Jahrom Branch, Islamic Azad University, Jahrom, Iran.
Samaneh ZolghadriDepartment of Microbiology, Jahrom Branch, Islamic Azad University, Jahrom, Iran.
Hasan HosainzadeganDepartment of Microbiology, Maragheh University of Medical Sciences, Maragheh, Iran.
Islamic Azad University, Jahrom Branch · IRUniversity of Maragheh · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMATERIALS AND

methodsExotoxin A was first extracted and purified from the culture medium of

resultsThe results indicated that nano-gold particles can be conjugated to the native exotoxin A with high efficiency. Immunogenicity investigation demonstrated that antibody titers produced against native exotoxin A and its conjugate to nano-gold particles are significant in a mouse model (

conclusionOur study indicated that exotoxin A can be produced with acceptable purity in the laboratory, and conjugated to gold nanoparticles. Based on these results nano-gold-exotoxin A conjugate is highly immunogenic and can be considered a potential vaccine candidate for

Indexed as

Exotoxin AGold nanoparticlesImmunizationPseudomonas aeruginosaVaccine candidate

Identifiers

PMID35096294
PMCPMC8769522
OpenAlexW3200849668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.