ReviewOxidative medicine and cellular longevity2022
A Common Feature of Pesticides: Oxidative Stress-The Role of Oxidative Stress in Pesticide-Induced Toxicity.
Review in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 178 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
178 citing papers in PubMed, 3 syntheses or guidelines pooled it, 483 citations in OpenAlex.
- Assessing the combined impact of pesticide exposure and HIV/ART on child neurodevelopment in Eastern and Southern Africa: a systematic review.BMC pediatrics · 2025Pooled it
- The impact of chemical pollution across major life transitions: a meta-analysis on oxidative stress in amphibians.Proceedings. Biological sciences · 2024Pooled it
- Oxidative balance score and risk of cancer: a systematic review and meta-analysis of observational studies.BMC cancer · 2023Pooled it
- Evaluation of Liver Biomarker Levels in Farmers Occupationally Exposed to Pesticides: A Cross-Sectional Study.Diseases (Basel, Switzerland) · 2026Article
- Comparative larvicidal efficacy and phytochemical profiling of selected Solanaceous hexane extracts against Culex pipiens and Aedes aegypti.Scientific reports · 2026Article
- Protective effects of rosmarinic acid against carbaryl-exposed toxicity in honey bees (Apis mellifera): histopathological and molecular docking evidence.Veterinary research communications · 2026Article
- Association between pesticide use and liver injury: A field study in Taiwan.Scandinavian journal of work, environment & health · 2026Article
- NADPH oxidases in immunometabolism and disease pathology: mechanistic networks, pollutant triggers, and therapeutic frontiers.Cellular & molecular immunology · 2026Review
- Occupational exposure to 2,4-dichlorophenoxyacetic acid (2,4-D) and associated oxidative and genomic biomarkers among soybean farmers: a cross-sectional study.Journal, genetic engineering & biotechnology · 2026Article
- mGem: A tale as old as blood-do tick-borne pathogens exploit arthropod antioxidant defenses?mBio · 2026Review
- Enhanced polyphenolic production in tissue culture-derived Opuntia ficus-indica increases larvicidal activity against Spodoptera exigua: biochemical, histological and molecular docking evidence.Scientific reports · 2026Article
- Serum Molecular Fingerprints of Oxidative Stress Underlying Neurocognitive and Motor Dysfunction in Pesticide-Exposed Populations.The European journal of neuroscience · 2026Article
- Integrated Transcriptomic and Metabolomic Analyses Reveal Early Concentration-Dependent Responses ofGenes · 2026Article
- Mitochondrial Toxicology of Heavy Metals and Pesticides: Transport Systems, Mitochondrial Dysfunction and Permeability Transition.International journal of molecular sciences · 2026Review
- Synergistic reproductive toxicity of lambda-cyhalothrin and thiamethoxam via oxidative stress and blood-testis barrier dysfunction in rats.Scientific reports · 2026Article
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- Enhanced Protection Against Toxicity ofToxins · 2026Article
- Dirty Earth, Diseased Hearts: Soil, Water, and Plastic Pollution in the Cardiovascular Exposome.Anatolian journal of cardiology · 2026Article
- Molecular and Biochemical Characterization of Insecticide Resistance in Field-CaughtACS omega · 2026Article
118 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Pesticides are important chemicals or biological agents that deter or kill pests. The use of pesticides has continued to increase as it is still considered the most effective method to reduce pests and increase crop growth. However, pesticides have other consequences, including potential toxicity to humans and wildlife. Pesticides have been associated with increased risk of cardiovascular disease, cancer, and birth defects. Labels on pesticides also suggest limiting exposure to these hazardous chemicals. Based on experimental evidence, various types of pesticides all seem to have a common effect, the induction of oxidative stress in different cell types and animal models. Pesticide-induced oxidative stress is caused by both reactive oxygen species (ROS) and reactive nitrogen species (RNS), which are associated with several diseases including cancer, inflammation, and cardiovascular and neurodegenerative diseases. ROS and RNS can activate at least five independent signaling pathways including mitochondrial-induced apoptosis. Limited
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.