ReviewInternational journal of exercise science2021
Isometric Exercise Training: A Review of Hypothesized Mechanisms and Protocol Application in Persons with Hypertension.
Review in International journal of exercise science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.
- The Optimal Dosage of Isometric Handgrip Exercise for Blood Pressure Reduction: Systematic Review and Meta-Analysis.Journal of clinical hypertension (Greenwich, Conn.) · 2026Pooled it
- OCTA Signal Quality Augmentation Using the Isometric Handgrip Test to Maximize Vascular Flow (SQUEEZE): A Randomized Crossover Trial.Translational vision science & technology · 2024Trial
- Optimal Exercise Modalities and Dosages for Blood Pressure Reduction in Adults With Prehypertension and Established Hypertension: A Network Meta-Analysis and Dose-Response Relationship Study.Journal of the American Heart Association · 2026Review
- Isometric handgrip exercise impacts only on very short-term blood pressure variability, but not on short-term blood pressure variability in hypertensive individuals: A randomized controlled trial.Frontiers in physiology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
According to the American Heart Association 116.4 million, or 46% of US adults are estimated to have hypertension. Although, traditional moderate intensity aerobic exercise training is associated with reducing blood pressure by 5-8 mmHg, barriers to this modality of exercise training exist. Thus, the purpose of this review is to evaluate the mechanisms and incorporation of isometric exercise training (IET) as an adjunctive mode of exercise in a population with HTN. Based upon the articles reviewed from the years 2000-2020 which incorporated IET and provided clear protocols lasting 4 or more weeks, meaningful reductions in blood pressure occurred following IET (SBP, -9.7 ± 3.3 mmHg; DBP, -4.8 ± 2.6 mmHg) which support the need to increase adoption of this exercise form into practice to help treat hypertension. Specifically, an IET program of 12-20 minutes per day, 3 times per week, could improve blood pressure reduction in those with hypertension. IET has the potential to produce significant and clinically meaningful blood pressure reductions and could serve as an adjunctive exercise modality alongside the established exercise prescription for those with hypertension.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.