Evidence map›Paper›PMID 35096135›Full record

ArticleComputational and mathematical methods in medicine2022

Intelligent Segmentation Medical Assistance System for MRI Images of Osteosarcoma in Developing Countries.

Jia Wu, Shun Yang, Fangfang Gou, Zhixun Zhou, Peng Xie, Nuo Xu, Zhehao Dai

Abstract read
In one paragraph

Article in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jia WuSchool of Computer Science and Engineering, Central South University, Chang sha 410083, China.ORCID https://orcid.org/0000-0001-9013-0818
Shun YangDepartment of Spine Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, China.
Fangfang GouSchool of Computer Science and Engineering, Central South University, Chang sha 410083, China.
Zhixun ZhouSchool of Computer Science and Engineering, Central South University, Chang sha 410083, China.
Peng XieDepartment of Spine Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, China.
Nuo XuDepartment of Spine Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, China.
Zhehao DaiDepartment of Spine Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, China.ORCID https://orcid.org/0000-0001-9285-2494

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma is the most common primary malignant bone tumor in children and adolescents. It has a high degree of malignancy and a poor prognosis in developing countries. The doctor manually explained that magnetic resonance imaging (MRI) suffers from subjectivity and fatigue limitations. In addition, the structure, shape, and position of osteosarcoma are complicated, and there is a lot of noise in MRI images. Directly inputting the original data set into the automatic segmentation system will bring noise and cause the model's segmentation accuracy to decrease. Therefore, this paper proposes an osteosarcoma MRI image segmentation system based on a deep convolution neural network, which solves the overfitting problem caused by noisy data and improves the generalization performance of the model. Firstly, we use Mean Teacher to optimize the data set. The noise data is put into the second round of training of the model to improve the robustness of the model. Then, we segment the image using a deep separable U-shaped network (SepUNet) and conditional random field (CRF). SepUnet can segment lesion regions of different sizes at multiple scales; CRF further optimizes the boundary. Finally, this article calculates the area of the tumor area, which provides a more intuitive reference for assisting doctors in diagnosis. More than 80000 MRI images of osteosarcoma from three hospitals in China were tested. The results show that the proposed method guarantees the balance of speed, accuracy, and cost under the premise of improving accuracy.

Indexed as

AlgorithmsAdolescentAdultArtificial IntelligenceBone NeoplasmsChinaComputational BiologyDatabases, FactualDeep LearningDeveloping CountriesFemaleHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleNeural Networks, Computer

Identifiers

PMID35096135
PMCPMC8791734

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.