Evidence map›Paper›PMID 35096062›Full record

ArticleJournal of oncology2022

Exosome-Mediated miR-4792 Transfer Promotes Bladder Cancer Cell Proliferation via Enhanced FOXC1/c-Myc Signaling and Warburg Effect.

Jian-Hong Wu, Ke-Ning Sun, Zhi-Hao Chen, Yi-Jun He, Lu Sheng

Open access · hybridAbstract read
In one paragraph

Article in Journal of oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Bladder cancer: non-coding RNAs and exosomal non-coding RNAs.Functional & integrative genomics · 2024
    Review
  5. Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jian-Hong WuDepartment of Urology, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.ORCID https://orcid.org/0000-0002-4401-2789
Ke-Ning SunDepartment of Urology, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.ORCID https://orcid.org/0000-0003-4520-6953
Zhi-Hao ChenDepartment of Urology, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.ORCID https://orcid.org/0000-0002-8201-0960
Yi-Jun HeDepartment of Urology, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.ORCID https://orcid.org/0000-0002-4710-0194
Lu ShengDepartment of Urology, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.ORCID https://orcid.org/0000-0003-3596-4136
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bladder cancer is the second-most common malignancy in the urogenital system and the most common in men. However, our understanding of the driving mechanisms of bladder cancer remains incomplete. The forkhead box (FOX) family of transcription factors is implicated in urogenital development and bladder malignancies. Many exosomal microRNAs have been identified as regulators and mediators of the expression of FOX, including the expression of FOXC1. miR-4792 has been known as a tumor miRNA suppressor. However, the function of miR-4792/FOXC1 signaling in bladder cancer development remains unknown. Here, we studied the role of miR-4792/FOXC1 signaling in bladder cancer by using multiple bladder cancer cell lines and bladder cancer mouse models through

Identifiers

PMID35096062
PMCPMC8791735
OpenAlexW4206671044

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.