Evidence map›Paper›PMID 35095919›Full record

ArticleFrontiers in immunology2021

Systematic Evaluation of

Vera Rebmann, Esther Schwich, Rafael Tomoya Michita, Lisa Grüntkemeier, Ann-Kathrin Bittner, Hana Rohn, Peter A Horn, Oliver Hoffmann, Rainer Kimmig, Sabine Kasimir-Bauer

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Vera RebmannInstitute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Esther SchwichInstitute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Rafael Tomoya MichitaInstitute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Lisa GrüntkemeierDepartment of Gynecology and Obstetrics, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Ann-Kathrin BittnerDepartment of Gynecology and Obstetrics, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Hana RohnDepartment of Infectious Diseases, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Peter A HornInstitute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Oliver HoffmannDepartment of Gynecology and Obstetrics, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Rainer KimmigDepartment of Gynecology and Obstetrics, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Sabine Kasimir-BauerDepartment of Gynecology and Obstetrics, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
University of Duisburg-Essen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite major improvements in diagnostics and therapy in early as well as in locally advanced breast cancer (LABC), metastatic relapse occurs in about 20% of patients, often explained by early micro-metastatic spread into bone marrow by disseminated tumor cells (DTC). Although neoadjuvant chemotherapy (NACT) has been a successful tool to improve overall survival (OS), there is growing evidence that various environmental factors like the non-classical human leukocyte antigen-G (HLA-G) promotes cancer invasiveness and metastatic progression. HLA-G expression is associated with regulatory elements targeting certain single-nucleotide polymorphisms (SNP) in the

Indexed as

3' Untranslated RegionsGenetic VariationAdolescentAdultAgedAged, 80 and overAllelesBiomarkers, TumorBreast NeoplasmsFemaleGenetic Association StudiesGenetic Predisposition to DiseaseGenotypeHaplotypesHLA-G AntigensHumans3' Untranslated RegionsBiomarkers, TumorHLA-G Antigensbreast cancerHLA-GHLA-G 3’UTR polymorphismHLA-G UTR-1HLA-G UTR-2HLA-G UTR-4

Identifiers

PMID35095919
PMCPMC8790528
OpenAlexW4206037631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.