Evidence map›Paper›PMID 35095871›Full record

ArticleFrontiers in immunology2021

Neutrophils Lose the Capacity to Suppress T Cell Proliferation Upon Migration Towards Inflamed Joints in Juvenile Idiopathic Arthritis.

Sabine Arve-Butler, Anki Mossberg, Tobias Schmidt, Charlotte Welinder, Hong Yan, Elisabet Berthold, Petra Król, Robin Kahn

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sabine Arve-ButlerDepartment of Rheumatology, Clinical Sciences Lund, Lund University, Lund, Sweden.
Anki MossbergWallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.
Tobias SchmidtWallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.
Charlotte WelinderDepartment of Clinical Sciences, Division of Oncology, Lund University, Lund, Sweden.
Hong YanSwedish National Infrastructure for Biological Mass Spectrometry, Biological Mass Spectrometry (BioMS), Lund, Sweden.
Elisabet BertholdDepartment of Rheumatology, Clinical Sciences Lund, Lund University, Lund, Sweden.
Petra KrólDepartment of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden.
Robin KahnWallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.
Lund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutrophils are highly abundant in synovial fluid of rheumatic inflamed joints. In oligoarticular juvenile idiopathic arthritis (JIA), synovial fluid neutrophils have impaired effector functions and altered phenotype. We hypothesized that these alterations might impact the immunoregulatory interplay between neutrophils and T cells. In this study we analyzed the suppressive effect of neutrophils, isolated from blood and synovial fluid of oligoarticular JIA patients, on CD4

Indexed as

AdolescentArthritis, JuvenileBiomarkersCell CommunicationCell MovementCells, CulturedChildChild, PreschoolFemaleHumansImmunomodulationLymphocyte ActivationMaleNeutrophilsPhenotypeProteomeBiomarkersProteomeReactive Oxygen Speciesjuvenile idiopathic arthritisneutrophilreactive oxygen speciessuppressionT cell

Identifiers

PMID35095871
PMCPMC8792960
OpenAlexW4205802447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.