Evidence map›Paper›PMID 35095819›Full record

ArticleFrontiers in microbiology2021

Genome Mining Shows Ubiquitous Presence and Extensive Diversity of Toxin-Antitoxin Systems in

Prem P Kandel, Marina Naumova, Chad Fautt, Ravikumar R Patel, Lindsay R Triplett, Kevin L Hockett

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Genomic profiling ofMicrobiology spectrum · 2026
    Article
  3. Development of a Potent and FunctionalJournal of medicinal chemistry · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Complete genome sequence ofFrontiers in microbiology · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Prem P KandelDepartment of Plant Pathology and Environmental Microbiology, Pennsylvania State University, University Park, PA, United States.
Marina NaumovaDepartment of Plant Pathology and Environmental Microbiology, Pennsylvania State University, University Park, PA, United States.
Chad FauttDepartment of Plant Pathology and Environmental Microbiology, Pennsylvania State University, University Park, PA, United States.
Ravikumar R PatelDepartment of Plant Pathology and Ecology, The Connecticut Agricultural Experiment Station, New Haven, CT, United States.
Lindsay R TriplettDepartment of Plant Pathology and Ecology, The Connecticut Agricultural Experiment Station, New Haven, CT, United States.
Kevin L HockettDepartment of Plant Pathology and Environmental Microbiology, Pennsylvania State University, University Park, PA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial toxin-antitoxin (TA) systems consist of two or more adjacent genes, encoding a toxin and an antitoxin. TA systems are implicated in evolutionary and physiological functions including genome maintenance, antibiotics persistence, phage defense, and virulence. Eight classes of TA systems have been described, based on the mechanism of toxin neutralization by the antitoxin. Although studied well in model species of clinical significance, little is known about the TA system abundance and diversity, and their potential roles in stress tolerance and virulence of plant pathogens. In this study, we screened the genomes of 339 strains representing the genetic and lifestyle diversity of the

Indexed as

genomicsphylogroupPseudomonas syringaestresstoxin-antitoxin systems

Identifiers

PMID35095819
PMCPMC8790059

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.