Evidence map›Paper›PMID 35095798›Full record

ArticleFrontiers in microbiology2021

Experimental Designs to Study the Aggregation and Colonization of Biofilms by Video Microscopy With Statistical Confidence.

Brian A Pettygrove, Heidi J Smith, Kyler B Pallister, Jovanka M Voyich, Philip S Stewart, Albert E Parker

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brian A PettygroveCenter for Biofilm Engineering, Montana State University, Bozeman, MT, United States.
Heidi J SmithCenter for Biofilm Engineering, Montana State University, Bozeman, MT, United States.
Kyler B PallisterDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, MT, United States.
Jovanka M VoyichDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, MT, United States.
Philip S StewartCenter for Biofilm Engineering, Montana State University, Bozeman, MT, United States.
Albert E ParkerCenter for Biofilm Engineering, Montana State University, Bozeman, MT, United States.

Funding

Tracking and Evaluation CoreU54GM115371 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI HOPKINS, SCARLETT H · 2016 to 2020
$20.9M
Defining SaeR/S-dependent Neutrophil-S. aureus Interactions that Determine the Outcome of InfectionR01AI149491 · NIAID · MONTANA STATE UNIVERSITY - BOZEMAN · PI NYGAARD, TYLER K, VOYICH, JOVANKA M · 2020 to 2024
$3.1M
How Do a Few Attached Staphylococcus aureus Bacteria Evade Innate Immunity to Initiate Biofilm Infection on an Implanted Medical Device?R56AI155692 · NIAID · MONTANA STATE UNIVERSITY - BOZEMAN · PI STEWART, PHILIP S · 2021 to 2021
$511k
NIAID NIH HHS R01 AI149491NIAID NIH HHS R56 AI155692NIGMS NIH HHS U54 GM115371
6 · The paper itself

Abstract

The goal of this study was to quantify the variability of confocal laser scanning microscopy (CLSM) time-lapse images of early colonizing biofilms to aid in the design of future imaging experiments. To accomplish this a large imaging dataset consisting of 16 independent CLSM microscopy experiments was leveraged. These experiments were designed to study interactions between human neutrophils and single cells or aggregates of

Indexed as

biofilmexperimental designimage analysismicroscopyrepeatabilitystatistical confidence

Identifiers

PMID35095798
PMCPMC8793059

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.