Evidence map›Paper›PMID 35095576›Full record

ArticleFrontiers in physiology2021

Gamma-Aminobutyric Acid Transporters in the Nucleus Tractus Solitarii Regulate Inhibitory and Excitatory Synaptic Currents That Influence Cardiorespiratory Function.

Diana Martinez, Ludmila Lima-Silveira, Michael P Matott, Eileen M Hasser, David D Kline

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Vagal GABAergic signaling in autonomic control of cardiometabolic function.American journal of physiology. Cell physiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Diana MartinezDepartment of Biomedical Sciences and Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO, United States.
Ludmila Lima-SilveiraDepartment of Biomedical Sciences and Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO, United States.
Michael P MatottDepartment of Biomedical Sciences and Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO, United States.
Eileen M HasserDepartment of Biomedical Sciences and Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO, United States.
David D KlineDepartment of Biomedical Sciences and Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO, United States.
University of Missouri · US

Funding

Neurophysiology and plasticity of cardiorespiratory circuits to hypoxiaR01HL128454 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI KLINE, DAVID DOUGLAS · 2016 to 2019
$2.0M
NHLBI NIH HHS R01 HL128454
6 · The paper itself

Abstract

The brainstem nucleus tractus solitarii (nTS) processes and modulates the afferent arc of critical peripheral cardiorespiratory reflexes. Sensory afferents release glutamate to initiate the central component of these reflexes, and glutamate concentration is critically controlled by its removal

Indexed as

autonomic nervous systemGABAglutamatesympathetic nervous systemsynaptic transmission

Identifiers

PMID35095576
PMCPMC8795970
OpenAlexW4210641979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.