Evidence map›Paper›PMID 35095560›Full record

ReviewFrontiers in physiology2021

Structural and Functional Coupling of Calcium-Activated BK Channels and Calcium-Permeable Channels Within Nanodomain Signaling Complexes.

Kunal R Shah, Xin Guan, Jiusheng Yan

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Potential therapeutic targeting of BKMolecular oncology · 2026
    Review
  4. Article
  5. Review
  6. Pro-tumoral CaScientific reports · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Evaluation of fourChannels (Austin, Tex.) · 2024
    Article
  13. Piezo1, the new actor in cell volume regulation.Pflugers Archiv : European journal of physiology · 2024
    Review
  14. The Variety of Mechanosensitive Ion Channels in Retinal Neurons.International journal of molecular sciences · 2024
    Review
  15. SOCE as a regulator of neuronal activity.The Journal of physiology · 2024
    Review
  16. Review
  17. Review
  18. Large conductance voltage-and calcium-activated KFrontiers in pharmacology · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kunal R ShahDepartment of Anesthesiology & Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Xin GuanDepartment of Anesthesiology & Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Jiusheng YanDepartment of Anesthesiology & Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
The University of Texas MD Anderson Cancer Center · US

Funding

BK channel regulation by auxiliary LRR proteinsR01NS078152 · NINDS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI YAN, JIUSHENG · 2012 to 2022
$3.5M
NINDS NIH HHS R01 NS078152
6 · The paper itself

Abstract

Biochemical and functional studies of ion channels have shown that many of these integral membrane proteins form macromolecular signaling complexes by physically associating with many other proteins. These macromolecular signaling complexes ensure specificity and proper rates of signal transduction. The large-conductance, Ca

Indexed as

BK channelscalcium-activated channelscalcium channelscalcium signalingcouplingnanodomainNMDA receptors

Identifiers

PMID35095560
PMCPMC8795833
OpenAlexW4206452382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.