Evidence map›Paper›PMID 35095526›Full record

ArticleFrontiers in pharmacology2021

Action of Varespladib (LY-315920), a Phospholipase A

Pamella G Gutierres, Diego R Pereira, Nataly L Vieira, Lilian F Arantes, Nelson J Silva, Kristian A Torres-Bonilla, Stephen Hyslop, Karen Morais-Zani, Rosa M B Nogueira, Edward G Rowan and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Integrated computational investigation ofFrontiers in molecular biosciences · 2026
    Article
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Pamella G GutierresLaboratory of Toxinology and Cardiovascular Research, University of Western São Paulo, Presidente Prudente, Brazil.
Diego R PereiraLaboratory of Toxinology and Cardiovascular Research, University of Western São Paulo, Presidente Prudente, Brazil.
Nataly L VieiraLaboratory of Toxinology and Cardiovascular Research, University of Western São Paulo, Presidente Prudente, Brazil.
Lilian F ArantesGraduate Program in Zootechnics, Rural Federal University of Pernambuco, Recife, Brazil.
Nelson J SilvaGraduate Program in Environmental Sciences and Health, School of Medical, Pharmaceutical and Biomedical Sciences, Pontifical Catholic University of Goiás, Goiânia, Brazil.
Kristian A Torres-BonillaDepartment of Pharmacology, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil.
Stephen HyslopDepartment of Pharmacology, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil.
Karen Morais-ZaniLaboratory of Herpetology, Butantan Institute, São Paulo, Brazil.
Rosa M B NogueiraLaboratory of Toxinology and Cardiovascular Research, University of Western São Paulo, Presidente Prudente, Brazil.
Edward G RowanStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.
Rafael S FlorianoLaboratory of Toxinology and Cardiovascular Research, University of Western São Paulo, Presidente Prudente, Brazil.
Universidade do Oeste Paulista · BRUniversidade Estadual de Campinas (UNICAMP) · BRInstituto Butantan · BRPontifícia Universidade Católica de Goiás · BRUniversidade Federal Rural de Pernambuco · BRUniversity of Strathclyde · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Varespladib (VPL) was primarily developed to treat inflammatory disturbances associated with high levels of serum phospholipase A

Indexed as

antivenomcoagulating activityhaemorrhageneutralizationphospholipase A2 (PLA2)varespladibViperidae snake

Identifiers

PMID35095526
PMCPMC8790531
OpenAlexW4206220970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.