ReviewFrontiers in pharmacology2021
Tannins as Hemostasis Modulators.
Review in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06687824 (Evaluation of the Effect of Black Tea Extract-Impregnated Gauze on Primary Bleeding Cessation After Molar Extraction), which is not on this map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Effect of Black Tea Extract-Impregnated Gauze on Primary Bleeding Cessation After Molar Extraction: A Randomized Controlled Trial
Who cites it
18 citing papers in PubMed, 47 citations in OpenAlex.
- Review
- Zein-based polysaccharide-tannic acid films as multifunctional barriers to prevent post-surgical adhesions.International journal of pharmaceutics: X · 2026Article
- A Review of Medicinal Plants from the Anak Dalam Tribe of Jambi: An Evaluation of Their Potential for Diabetic Wound Healing Effects-Current Status and Future Perspectives.Drug design, development and therapy · 2026Review
- Cytotoxicity and Coagulation Effects of Methanolic Extracts ofJournal of experimental pharmacology · 2026Article
- Integrating Biosensors in Phytochemical Research: Challenges and Breakthroughs.Recent patents on biotechnology · 2026Review
- Tannic acid modified horizontal platelet-rich fibrin membrane with improved mechanical and biological properties for tissue regeneration : Author full names.Scientific reports · 2025Article
- Article
- Galloylated polyphenols represent a new class of antithrombotic agents with broad activity against thiol isomerases.Journal of thrombosis and haemostasis : JTH · 2025Article
- Tea Bags for Controlling Postoperative Bleeding after Extraction of Teeth: A Review of Literature.Journal of pharmacy & bioallied sciences · 2025Review
- Procyanidin displayed a synergistic effect with roxadustat on renal anemia in mice.Frontiers in pharmacology · 2025Article
- Hepatoprotective, Lipid-Lowering and Antioxidant Effects of Mangaba Powder (Foods (Basel, Switzerland) · 2024Article
- Efficacy of a vaginal suppository formulation prepared withFrontiers in pharmacology · 2024Article
- The application of rhubarb concoctions in traditional Chinese medicine and its compounds, processing methods, pharmacology, toxicology and clinical research.Frontiers in pharmacology · 2024Review
- The SAR analysis of dietary polyphenols and their antagonistic effects on bortezomib at physiological concentrations.Frontiers in pharmacology · 2024Article
- Chitosan-PEG Gels Loaded withPharmaceuticals (Basel, Switzerland) · 2023Article
- Plant-Derived Compounds and Extracts as Modulators of Plasmin Activity-A Review.Molecules (Basel, Switzerland) · 2023Review
- Recognition of Gallotannins and the Physiological Activities: From Chemical View.Frontiers in nutrition · 2022Review
- Phytochemicals profile, cellular viabillity and platelet activity ofJournal of oral biology and craniofacial researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The hemostasis system is often affected by complications associated with cardiovascular diseases, which results in thromboembolic events. Compounds of plant origin and plant extracts are considered as a promising source of substances that could modulate the functioning of the hemostasis system and thus reduce the risk of thromboembolism. Among them, tannins, which are plant-origin compounds with potential effects in hemostasis, deserve a special mention. This paper describes the hemostasis-modifying ability of three groups of tannins, namely ellagitannins, gallotannins, and procyanidins. The review highlights the desirable as well as undesirable influence of tannins on specific components of hemostasis, namely platelets, coagulation system, fibrinolysis system, and endothelium, and the multidirectional effect of these compounds on the thrombotic process. Studies performed under normal and pathological conditions such as diabetes or hypercoagulation are described, and the pathophysiology-dependent action of tannins is also highlighted. Most of the studies presented in the paper were performed
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.