Evidence map›Paper›PMID 35095499›Full record

ArticleFrontiers in pharmacology2021

The Tarantula Venom Peptide Eo1a Binds to the Domain II S3-S4 Extracellular Loop of Voltage-Gated Sodium Channel Na

Jennifer R Deuis, Lotten Ragnarsson, Samuel D Robinson, Zoltan Dekan, Lerena Chan, Ai-Hua Jin, Poanna Tran, Kirsten L McMahon, Shengnan Li, John N Wood and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Electrostatic tuning of NaThe Journal of physiology · 2026
    Article
  2. The Excelsatoxin A-Receptor TMEM233 Modulates Nav1.8.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Jennifer R DeuisInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
Lotten RagnarssonInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
Samuel D RobinsonInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
Zoltan DekanInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
Lerena ChanInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
Ai-Hua JinInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
Poanna TranInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
Kirsten L McMahonInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
Shengnan LiWolfson Institute for Biomedical Research, University College London, London, United Kingdom.
John N WoodWolfson Institute for Biomedical Research, University College London, London, United Kingdom.
James J CoxWolfson Institute for Biomedical Research, University College London, London, United Kingdom.
Glenn F KingInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
Volker HerzigGeneCology Research Centre, University of the Sunshine Coast, Sippy Downs, QLD, Australia.
Irina VetterInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
University of Queensland · AUWolfson Foundation · GBUniversity College London · GBUniversity of the Sunshine Coast · AU

Funding

Medical Research Council MR/R011737/1Versus Arthritis 21950Wellcome Trust 200183/Z/15/Z
6 · The paper itself

Abstract

Venoms from cone snails and arachnids are a rich source of peptide modulators of voltage-gated sodium (Na

Indexed as

Nav1.8painpeptidespidervoltage-gated sodium channel

Identifiers

PMID35095499
PMCPMC8795738
OpenAlexW4206115049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.