Evidence map›Paper›PMID 35095496›Full record

ArticleFrontiers in pharmacology2021

Sex-Specific Differences in Resolution of Airway Inflammation in

Arzu Ulu, Jalene V Velazquez, Abigail Burr, Stefanie N Sveiven, Jun Yang, Carissa Bravo, Bruce D Hammock, Tara M Nordgren

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Arzu UluDivision of Biomedical Sciences, School of Medicine, University of California, Riverside, Riverside, CA, United States.
Jalene V VelazquezDivision of Biomedical Sciences, School of Medicine, University of California, Riverside, Riverside, CA, United States.
Abigail BurrDivision of Biomedical Sciences, School of Medicine, University of California, Riverside, Riverside, CA, United States.
Stefanie N SveivenDivision of Biomedical Sciences, School of Medicine, University of California, Riverside, Riverside, CA, United States.
Jun YangDepartment of Entomology and Nematology, University of California Davis Comprehensive Cancer Center, University of California, Davis, Davis, CA, United States.
Carissa BravoDivision of Biomedical Sciences, School of Medicine, University of California, Riverside, Riverside, CA, United States.
Bruce D HammockDepartment of Entomology and Nematology, University of California Davis Comprehensive Cancer Center, University of California, Davis, Davis, CA, United States.
Tara M NordgrenDivision of Biomedical Sciences, School of Medicine, University of California, Riverside, Riverside, CA, United States.
University of California, Riverside · USUniversity of California, Davis · US

Funding

Workshop on Environmental Technology Transfer and EntrepreneurshipP42ES004699 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI HAMMOCK, BRUCE D · 1987 to 2021
$50.1M
Supplement for bioactive lipids as effectors and indicators of the deleterious effects of human healthR35ES030443 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MORISSEAU, CHRISTOPHE HP · 2019 to 2025
$5.8M
Omega-3 fatty acids induce macrophage IL-22 signaling to promote resolution of dust-induced lung inflammationR01HL158926 · NHLBI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI NORDGREN, TARA M · 2021 to 2025
$2.5M
The role of omega-3 fatty acids and bioactive lipid signaling in airway inflammation and resolution following organic dust exposuresR00ES025819 · NIEHS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI NORDGREN, TARA M · 2017 to 2019
$747k
NHLBI NIH HHS R01 HL158926NIEHS NIH HHS P42 ES004699NIEHS NIH HHS R00 ES025819NIEHS NIH HHS R35 ES030443
6 · The paper itself

Abstract

In agriculture industries, workers are at increased risk for developing pulmonary diseases due to inhalation of agricultural dusts, particularly when working in enclosed confinement facilities. Agricultural dusts inhalation leads to unresolved airway inflammation that precedes the development and progression of lung disease. We have previously shown beneficial effects of the omega-3 polyunsaturated fatty acid (ω-3 PUFA) DHA in protecting against the negative inflammatory effects of repetitive dust exposure in the lung. Dietary manipulation of pulmonary disease risk is an attractive and timely approach given the contribution of an increased ω-6 to ω-3 PUFA ratio to low grade inflammation and chronic disease in the Western diet. To prevent any confounding factors that comes with dietary supplementation of ω-3 PUFA (different sources, purity, dose, and duration), we employed a

Indexed as

agricultural dustfat-1 transgenic miceomega-3 fatty acidsresolution of inflammationsex

Identifiers

PMID35095496
PMCPMC8793679
OpenAlexW4206671946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.