Evidence map›Paper›PMID 35095492›Full record

ArticleFrontiers in pharmacology2021

Molecular Mechanisms of Epileptic Encephalopathy Caused by KCNMA1 Loss-of-Function Mutations.

Yu Yao, Dongxiao Qu, Xiaoping Jing, Yuxiang Jia, Qi Zhong, Limin Zhuo, Xingxing Chen, Guoyi Li, Lele Tang, Yudan Zhu and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Circadian Control of Sleep by Melatonin via MTbioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Systems Genetics Analyses Reveals Key Genes Related to Behavioral Traits in the Striatum of CFW Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  7. BK Channelopathies andAnnual review of physiology · 2024
    Review
  8. Large conductance voltage-and calcium-activated KFrontiers in pharmacology · 2024
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Yu YaoSchool of Medicine and School of Life Sciences, Shanghai University, Shanghai, China.
Dongxiao QuDepartment of Neurology and Central Laboratory, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xiaoping JingDepartment of Traditional Chinese Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Yuxiang JiaSchool of Medicine and School of Life Sciences, Shanghai University, Shanghai, China.
Qi ZhongSchool of Medicine and School of Life Sciences, Shanghai University, Shanghai, China.
Limin ZhuoSchool of Medicine and School of Life Sciences, Shanghai University, Shanghai, China.
Xingxing ChenDepartment of Neurology and Central Laboratory, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Guoyi LiDepartment of Neurology and Central Laboratory, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Lele TangDepartment of Neurology and Central Laboratory, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yudan ZhuDepartment of Neurology and Central Laboratory, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xuemei ZhangDepartment of Pharmacology, School of Pharmacy, Fudan University, Shanghai, China.
Yonghua JiSchool of Medicine and School of Life Sciences, Shanghai University, Shanghai, China.
Zhiping LiDepartment of Clinical Pharmacy, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Jie TaoDepartment of Neurology and Central Laboratory, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Shanghai University of Traditional Chinese Medicine · CNShanghai University · CNChildren's Hospital of Fudan University · CNFudan University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gene

Indexed as

autophagyBK channelepilepsyKCNMA1loss-of-function variantsneuroinflammation

Identifiers

PMID35095492
PMCPMC8793784
OpenAlexW4205935265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.