Evidence map›Paper›PMID 35095348›Full record

ArticleJournal of interventional cardiology2022

Improved Outcomes of Combined Main Branch Stenting and Side Branch Drug-Coated Balloon versus Two-Stent Strategy in Patients with Left Main Bifurcation Lesions.

Hengdao Liu, Hailong Tao, Xufei Han, Yang Lu, Xiaofei Xue, Ruihan Feng, Fenghua Lv, Yanwei Liu, Hongrui Jin, Lianjie Li and 1 more

Abstract read
In one paragraph

Article in Journal of interventional cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. A Comparison of a Drug Coated Balloon With Drug Eluting Stent Strategy for Treating Coronary Bifurcation Lesions.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Application of Drug-Coated Balloons in Complex High Risk and Indicated Percutaneous Coronary Interventions.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Review
  9. Evaluation of FFR and CPET in patients withFrontiers in cardiovascular medicine · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. The Drug Coated Balloon-Only Strategy for Treatment of de Novo Left Main Coronary Artery Bifurcation Lesion: Stentless Strategy.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
  14. Safety and Efficacy of Drug-Coated Balloons in Patients with Acute Coronary Syndromes and Vulnerable Plaque.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hengdao LiuDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.
Hailong TaoDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.
Xufei HanDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.
Yang LuDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.
Xiaofei XueDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.
Ruihan FengDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.
Fenghua LvDepartment of Cardiology, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, China.
Yanwei LiuDepartment of Infectious Disease, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan 453100, China.
Hongrui JinDepartment of Magnetic Resonance, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Lianjie LiDepartment of Cardiology, Xichuan Second People's Hospital, Nanyang 474450, Henan, China.
Heping GuDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.ORCID https://orcid.org/0000-0002-1979-7449

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDrug-eluting stent (DES) plus drug-coated balloon (DCB) is a safe and effective treatment strategy for coronary artery bifurcation lesions, but there is no report about this strategy being used for left main (LM) bifurcation lesions. We aim to explore the efficacy and safety of DES plus DCB in the treatment of LM bifurcation lesions.

methodsA total of 100 patients diagnosed with LM bifurcation lesions by coronary angiography were retrospectively enrolled at our center from January 2018 to December 2019. They received either a two-stent strategy or a main branch (MB) stenting plus side branch (SB) DCB strategy and were accordingly divided into the 2-DES group and the DES + DCB group. Patients treated with DES + DCB were compared with a cohort of matched patients treated with a 2-DES strategy. Clinical data was collected and quantitative coronary analysis was performed.

resultsFor immediate postoperative angiography, though the two groups had no differences in the minimal luminal diameter (MLD) and luminal stenosis of MB, the DES + DCB group had significantly lower SB ostial MLD and a higher degree of residual lumen stenosis than the 2-DES group (

conclusionThe combination of DES and DCB is relatively safe and effective for the treatment of LM bifurcation lesions, and this strategy seems to have advantages in reducing LLL at the SB ostium.

Indexed as

Angioplasty, Balloon, CoronaryDrug-Eluting StentsPharmaceutical PreparationsHumansRetrospective StudiesStentsPharmaceutical Preparations

Identifiers

PMID35095348
PMCPMC8767379

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.