Evidence map›Paper›PMID 35095264›Full record

ReviewThe Egyptian journal of internal medicine2022

Acquired hemophilia A (AHA): underreported, underdiagnosed, undertreated medical condition.

Doaa M El Demerdash, Alia Ayad, Noha Tawfik

Abstract readReview
In one paragraph

Review in The Egyptian journal of internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Acquired hemophilia A secondary to cholangiocarcinoma: A case report and literature review.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Postpartum-acquired hemophilia A: case report.Revista peruana de medicina experimental y salud publica
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Doaa M El DemerdashInternal Medicine Department, Kasr Al-Ainy Hospital, Faculty of Medicine, Cairo University, Cairo, Egypt.ORCID 0000-0002-5061-9536
Alia AyadInternal Medicine Department, Kasr Al-Ainy Hospital, Faculty of Medicine, Cairo University, Cairo, Egypt.
Noha TawfikInternal Medicine Department, Kasr Al-Ainy Hospital, Faculty of Medicine, Cairo University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcquired hemophilia A (AHA) is a rare acquired bleeding disorder occurred due to the formation of inhibitory antibodies neutralizing endogenous factor VIII. MAIN BODY: About half the cases are idiopathic. Symptoms include severe and unexpected bleeding that could be life-threatening. High index of suspicion should be raised when unexplained subcutaneous or post-surgical bleeding with isolated prolonged APTT.

conclusionsAcquired hemophilia A is a rare underdiagnosed underreported acquired hemostatic disorder that presents with sudden usually life-threatening bleeding; it is crucial to raise awareness and suspicion index of clinicians for early diagnosis and treatment to avoid morbidity and mortality.

Indexed as

AcquiredBleedingHemophiliaProlonged APTT

Identifiers

PMID35095264
PMCPMC8788911

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.