Molecular docking analysis of CDK-1 inhibitors from Chrysophyllum cainito leaves.

Yesudass Antony Prabhu, Praveen Kumar Kumar, Shanmughavel Piramanayagam, Muthu Vijaya Sarathy, Samiappan Kavitha

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Article in Bioinformation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

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1 citing paper in PubMed.

Integrated Phytochemical Profiling, GC-MS Characterization, and In Silico, In Vitro Evaluation of Synergistic Antimicrobial, Antioxidant, and Anti-Inflammatory Activities ofAntioxidants (Basel, Switzerland) · 2025
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Authors and funding

5 authors.

Yesudass Antony PrabhuDepartment of Biochemistry, Rathnavel Subramaniam College of Arts and Science, Coimbatore - 641402, India.

Praveen Kumar KumarDepartment of Bioinformatics, Bharathiar University, Coimbatore - 641046, India.

Shanmughavel PiramanayagamDepartment of Bioinformatics, Bharathiar University, Coimbatore - 641046, India.

Muthu Vijaya SarathyDepartment of Microbial Biotechnology, Bharathiar University, Coimbatore - 641046, India.

Samiappan KavithaDepartment of Biochemistry, Rathnavel Subramaniam College of Arts and Science, Coimbatore - 641402, India.

Funding

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6 · The paper itself

Abstract

It is of interest to document the molecular docking analysis of Cyclin-dependent kinase 1 (CDK-1) inhibitors from Chrysophyllum cainito leaves towards the treatment of tumors using the known structure of PDB ID: 5HQ0. Data shows that molecules such as 8- (Dimethylamino)-7-(3-(4-ethylphenoxy)-2d, ethyl 6-oxo-5-propylheptanoate, 2,3-dihydro-3, 5-dihydroxy-6-methyl-4h-pyran-4-one, 1,2,3-benzenetriol and 1,4-benzenediol 2,5-bis (1,1-dimethylethyl) identified in methanolic extract of C. cainito have binding features with CDK1 for further consideration.

Indexed as

CDK-1Chrysophyllum cainitoOral squamous cell carcinomaSchrodinger

Identifiers

PMID35095229

DOI10.6026/97320630017550

PMCPMC8770403

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