ArticleJournal Of Elasticity2021
A Comparison of Fiber Based Material Laws for Myocardial Scar.
Article in Journal Of Elasticity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- The Impact of Standard Ablation Strategies for Atrial Fibrillation on Cardiovascular Performance in a Four-Chamber Heart Model.Cardiovascular engineering and technology · 2023Article
- Computationally Efficient Concept of Representative Directions for Anisotropic Fibrous Materials.Polymers · 2022Article
- Personalized biomechanical insights in atrial fibrillation: opportunities & challenges.Expert review of cardiovascular therapyReview
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The mechanics of most soft tissues in the human body are determined by the organization of their collagen fibers. Predicting how mechanics will change during growth and remodeling of those tissues requires constitutive laws that account for the density and dispersion of collagen fibers. Post-infarction scar in the heart, a mechanically and structurally complex material, does not yet have a validated fiber-based constitutive model. In this study, we tested four different constitutive laws employing exponential or polynomial strain-energy functions and accounting for either mean fiber orientation alone or the details of the fiber distribution about that mean. We quantified the goodness of fit of each law to mechanical testing data from 6-week-old myocardial scar in the rat using both sum of squared error (SSE) and the Akaike Information Criterion (AIC) to account for differences in the number of material parameters within the constitutive laws. We then compared their ability to prospectively predict the mechanics of independent myocardial scar samples from other time points during healing. Our analysis suggests that a constitutive law with a polynomial form that incorporates detailed information about collagen fiber distribution using a structure tensor provides excellent fits with just two parameters and reasonable predictions of myocardial scar mechanics from measured structure alone in scars containing sufficiently high collagen content.
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