Evidence map›Paper›PMID 35095059›Full record

ArticleThe Journal of veterinary medical science2022

Pharmacokinetics in plasma and alveolar regions of a healthy calf intramuscularly administered a single dose of orbifloxacin.

Tetsuro Kuramae, Shingo Ishikawa, Aki Kono, Seiji Hobo

Open access · diamondAbstract read
In one paragraph

Article in The Journal of veterinary medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Tetsuro KuramaeKuramae Animal Clinic, Kagoshima, Japan.
Shingo IshikawaUnited Graduate School of Veterinary Science, Yamaguchi University, Yamaguchi, Japan.
Aki KonoJoint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
Seiji HoboUnited Graduate School of Veterinary Science, Yamaguchi University, Yamaguchi, Japan.
Kagoshima University · JPYamaguchi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study analyzed the pharmacokinetics of orbifloxacin (OBFX) in plasma, and its migration and retention in epithelial lining fluid (ELF) and alveolar cells within the bronchoalveolar lavage fluid (BALF). Four healthy calves received a single dose of OBFX (5.0 mg/kg) intramuscularly. Post-administration OBFX dynamics were in accordance with a non-compartment model, including the absorption phase. The maximum concentration (C

Indexed as

Alveolar Epithelial CellsCiprofloxacinAnimalsAnti-Bacterial AgentsBronchoalveolar Lavage FluidCattleAnti-Bacterial AgentsCiprofloxacinorbifloxacinbronchoalveolar lavage fluidcalforbifloxacinpharmacodynamicpharmacokinetic

Identifiers

PMID35095059
PMCPMC8983296
OpenAlexW4210749183

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.