Evidence map›Paper›PMID 35094717›Full record

ArticlePsychological medicine2023

Prior differences in previous trauma exposure primarily drive the observed racial/ethnic differences in posttrauma depression and anxiety following a recent trauma.

N G Harnett, N M Dumornay, M Delity, L D Sanchez, K Mohiuddin, P I Musey, M J Seamon, S A McLean, R C Kessler, K C Koenen and 46 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Racial and ethnic socioenvironmental inequity and neuroimaging in psychiatry: a brief review of the past and recommendations for the future.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

56 authors at 20 institutions in 2 countries.

N G HarnettDivision of Depression and Anxiety, McLean Hospital, Belmont, MA 02478, USA.
N M DumornayDivision of Depression and Anxiety, McLean Hospital, Belmont, MA 02478, USA.
M DelityDivision of Depression and Anxiety, McLean Hospital, Belmont, MA 02478, USA.
L D SanchezDepartment of Emergency Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
K MohiuddinDepartment of Emergency Medicine, Einstein Medical Center, Philadelphia, PA 19141, USA.
P I MuseyDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
M J SeamonDepartment of Surgery, Division of Traumatology, Surgical Critical Care and Emergency Surgery, University of Pennsylvania, Pennsylvania, PA 19104, USA.
S A McLeanDepartment of Emergency Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27559, USA.ORCID 0000-0001-9482-3582
R C KesslerDepartment of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA.
K C KoenenDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115, USA.
F L BeaudoinDepartment of Emergency Medicine & Department of Health Services, Policy, and Practice, The Alpert Medical School of Brown University, Rhode Island Hospital and The Miriam Hospital, Providence, RI 02930, USA.
L A M LeboisDivision of Depression and Anxiety, McLean Hospital, Belmont, MA 02478, USA.
S J H van RooijDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30332, USA.
N A SampsonDepartment of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA.
V MichopoulosDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30332, USA.
J L Maples-KellerDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30332, USA.
J P HaranDepartment of Emergency Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA.
A B StorrowDepartment of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
C LewandowskiDepartment of Emergency Medicine, Henry Ford Health System, Detroit, MI 48202, USA.
P L HendryDepartment of Emergency Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, FL 32209, USA.
S SheikhDepartment of Emergency Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, FL 32209, USA.
C W JonesDepartment of Emergency Medicine, Cooper Medical School of Rowan University, Camden, NJ 08103, USA.
B E PunchesDepartment of Emergency Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
M C KurzDepartment of Emergency Medicine, University of Alabama School of Medicine, Birmingham, AL 35294, USA.
R A SworDepartment of Emergency Medicine, Oakland University William Beaumont School of Medicine, Rochester, MI 48309, USA.
M E McGrathDepartment of Emergency Medicine, Boston Medical Center, Boston, MA 02118, USA.
L A HudakDepartment of Emergency Medicine, Emory University School of Medicine, Atlanta, GA 30329, USA.
J L PascualDepartment of Surgery, Department of Neurosurgery, University of Pennsylvania, Pennsylvania, PA 19104, USA.
S L HouseDepartment of Emergency Medicine, Washington University School of Medicine, St. Louis, MO 63130, USA.
X AnDepartment of Anesthesiology, Institute for Trauma Recovery, University of North Carolina at Chapel Hill, Chapel Hill, NC 27559, USA.
J S StevensDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30329, USA.
T C NeylanDepartments of Psychiatry and Neurology, University of California San Francisco, San Francisco, CA 94143, USA.
T JovanovicDepartment of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, MI 48202, USA.
S D LinnstaedtDepartment of Anesthesiology, Institute for Trauma Recovery, University of North Carolina at Chapel Hill, Chapel Hill, NC 27559, USA.
L T GermineDepartment of Psychiatry, Harvard Medical School, Boston, MA 02115, USA.
E M DatnerDepartment of Emergency Medicine, Einstein Healthcare Network, Pennsylvania, PA 19141, USA.
A M ChangDepartment of Emergency Medicine, Jefferson University Hospitals, Pennsylvania, PA 19107, USA.
C PearsonDepartment of Emergency Medicine, Wayne State University, Detroit, MA 48202, USA.
D A PeakDepartment of Emergency Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
R C MerchantDepartment of Emergency Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
R M DomeierDepartment of Emergency Medicine, Saint Joseph Mercy Hospital, Ypsilanti, MI 48197, USA.
N K RathlevDepartment of Emergency Medicine, University of Massachusetts Medical School-Baystate, Springfield, MA 01107, USA.
B J O'NeilDepartment of Emergency Medicine, Wayne State University, Detroit, MA 48202, USA.
P SergotDepartment of Emergency Medicine, McGovern Medical School, University of Texas Health, Houston, TX 77030, USA.
S E BruceDepartment of Psychological Sciences, University of Missouri - St. Louis, St. Louis, MO 63121, USA.
M W MillerNational Center for PTSD, Behavioral Science Division, VA Boston Healthcare System, Boston, MA 02130, USA.
R H PietrzakNational Center for PTSD, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, CT 06516, USA.
J JoormannDepartment of Psychology, Yale University, West Haven, CT 06520, USA.
D M BarchDepartment of Psychological & Brain Sciences, Washington University in St. Louis, St. Louis, MO 63130, USA.
D A PizzagalliDivision of Depression and Anxiety, McLean Hospital, Belmont, MA 02478, USA.
J F SheridanDepartment of Biosciences, OSU Wexner Medical Center, Columbus, OH 43210, USA.
J W SmollerDepartment of Psychiatry, Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA.
B LunaAffiliation Laboratory of Neurocognitive Development, University of Pittsburgh Medical Center - Western Psychiatric Hospital, Pittsburgh, PA 15213, USA.
S E HarteDepartment of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
J M ElliottThe Kolling Institute, University of Sydney, St Leonards, New South Wales 2065, Australia.
K J ResslerDivision of Depression and Anxiety, McLean Hospital, Belmont, MA 02478, USA.
Harvard University · USEmory University · USUniversity of North Carolina at Chapel Hill · USWayne State University · USBrigham and Women's Hospital · USMcLean Hospital · USUniversity of Florida · USUniversity of Pennsylvania · USWashington University in St. Louis · USYale University · USBaystate Medical Center · USBoston Medical Center · USBoston University · USBroad Institute · USBrown University · USCooper Medical School of Rowan University · USEinstein Medical Center Philadelphia · USHenry Ford Health System · USIndiana University School of MedicineJefferson University Hospitals · US

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Longitudinal Assessment of Post-traumatic SyndromesU01MH110925 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KESSLER, RONALD C, KOENEN, KARESTAN C · 2016 to 2020
$25.8M
Training Program in Psychiatric Genetics and Translational ResearchT32MH017119 · NIMH · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI KARESTAN C KOENEN, Jukka-Pekka Onnela · 1985 to 2026
$8.9M
Early Life Stress and Depression: Molecular and Functional Imaging ApproachesR01MH095809 · NIMH · MCLEAN HOSPITAL · PI DU, FEI, PIZZAGALLI, DIEGO A · 2012 to 2024
$6.4M
Neuromuscular Mechanisms Underlying Poor Recovery from Whiplash InjuriesR01HD079076 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI COURTNEY, D. MARK, ELLIOTT, JAMES MATTHEW · 2014 to 2018
$1.6M
Characterizing the Neurobiology of Pathological Dissociation: Mechanisms of Face Perception and Self Referential ProcessingK01MH118467 · NIMH · MCLEAN HOSPITAL · PI LEBOIS, LAUREN ANN MCDONOUGH · 2019 to 2022
$679k
A Multidimensional Neuroimaging Investigation of Posttraumatic Stress in HumansK00MH119603 · NIMH · MCLEAN HOSPITAL · PI HARNETT, NATHANIEL G · 2018 to 2021
$311k
MRI and machine learning to improve early prognosis and clinical management after spinal cord injuryR03HD094577 · NICHD · UNIVERSITY OF COLORADO DENVER · PI SMITH, ANDREW CRAIG · 2019 to 2020
$195k
SOCIAL SUPPORT OF CAREGIVERS FOR DEMENTIA PATIENTSF33AG005654 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI SOKOLOVSKY, JAY H · 1994 to 1994
–
NIA NIH HHS F33 AG005654NICHD NIH HHS R01 HD079076NICHD NIH HHS R03 HD094577NIH HHS P51 OD011132NIMH NIH HHS K00 MH119603NIMH NIH HHS K01 MH118467NIMH NIH HHS R01 MH095809NIMH NIH HHS T32 MH017119NIMH NIH HHS U01 MH110925
6 · The paper itself

Abstract

backgroundRacial and ethnic groups in the USA differ in the prevalence of posttraumatic stress disorder (PTSD). Recent research however has not observed consistent racial/ethnic differences in posttraumatic stress in the early aftermath of trauma, suggesting that such differences in chronic PTSD rates may be related to differences in recovery over time.

methodsAs part of the multisite, longitudinal AURORA study, we investigated racial/ethnic differences in PTSD and related outcomes within 3 months after trauma. Participants (

resultsRacial/ethnic groups did not differ in symptoms over time; however, Black participants showed reduced posttraumatic depression and anxiety symptoms overall compared to Hispanic participants and White participants. Racial/ethnic differences were not attenuated after accounting for differences in sociodemographic factors. However, racial/ethnic differences in depression and anxiety were no longer significant after accounting for greater prior trauma exposure and childhood emotional abuse in White participants.

conclusionsThe present findings suggest prior differences in previous trauma exposure partially mediate the observed racial/ethnic differences in posttraumatic depression and anxiety symptoms following a recent trauma. Our findings further demonstrate that racial/ethnic groups show similar rates of symptom recovery over time. Future work utilizing longer time-scale data is needed to elucidate potential racial/ethnic differences in long-term symptom trajectories.

Indexed as

DepressionStress Disorders, Post-TraumaticAnxietyAnxiety DisordersChildEthnicityHumansanxietydepressionDisparitiesethnicityracetrauma

Identifiers

PMID35094717
PMCPMC9339026
OpenAlexW4210340770

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.