Evidence map›Paper›PMID 35094505›Full record

ArticleAnnals of clinical and translational neurology2022

Physical activity level and stroke risk in US population: A matched case-control study of 102,578 individuals.

Sherief Ghozy, Ahmad Helmy Zayan, Amr Ehab El-Qushayri, Kate Elizabeth Parker, Joseph Varney, Kevin M Kallmes, Sara Morsy, Alzhraa Salah Abbas, Jose Danilo B Diestro, Adam A Dmytriw and 3 more

Abstract read
In one paragraph

Article in Annals of clinical and translational neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Stroke burden and associated predictors: A methodological reflection.Aging clinical and experimental research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sherief GhozyDepartment of Neuroradiology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0001-5629-3023
Ahmad Helmy ZayanFaculty of Medicine, Menoufia University, Menoufia, Egypt.ORCID 0000-0003-2581-0459
Amr Ehab El-QushayriFaculty of Medicine, Minia University, Minia, Egypt.ORCID 0000-0002-0967-797X
Kate Elizabeth ParkerInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Melbourne, Vic., Australia.ORCID 0000-0002-8301-1391
Joseph VarneySchool of Medicine, American University of the Caribbean, Cupecoy, Sint Maarten.ORCID 0000-0003-1797-8016
Kevin M KallmesNested Knowledge, St. Paul, Minnesota, USA.ORCID 0000-0001-5439-4074
Sara MorsyMedical Biochemistry and Molecular Biology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.ORCID 0000-0002-2477-1139
Alzhraa Salah AbbasFaculty of Medicine, Minia University, Minia, Egypt.ORCID 0000-0003-3975-1496
Jose Danilo B DiestroRadiology Department, Central Hospital of University of Montreal, University of Montreal, Montreal, QC, Canada.ORCID 0000-0001-8450-2021
Adam A DmytriwNeuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0003-0131-5699
Jaffer ShahMedical Research Center, Kateb University, Kabul, Afghanistan.ORCID 0000-0002-8961-218X
Ameer E HassanDepartment of Neurology, University of Texas Rio Grande Valley, Harlingen, Texas, USA.ORCID 0000-0002-7148-7616
Sheikh Mohammed Shariful IslamInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Melbourne, Vic., Australia.ORCID 0000-0001-7926-9368

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStroke has been linked to a lack of physical activity; however, the extent of the association between inactive lifestyles and stroke risk has yet to be characterized across large populations. PURPOSE: This study aimed to explore the association between activity-related behaviors and stroke incidence.

methodsData from 1999 to 2018 waves of the concurrent cross-sectional National Health and Nutrition Examination Survey (NHANES) were extracted. We analyzed participants characteristics and outcomes for all participants with data on whether they had a stroke or not and assessed how different forms of physical activity affect the incidence of disease.

resultsOf the 102,578 individuals included, 3851 had a history of stroke. A range of activity-related behaviors was protective against stroke, including engaging in moderate-intensity work over the last 30 days (OR = 0.8, 95% CI = 0.7-0.9; P = 0.001) and vigorous-intensity work activities over the last 30 days (OR = 0.6, 95% CI = 0.5-0.8; P < 0.001), and muscle-strengthening exercises (OR = 0.6, 95% CI = 0.5-0.8; P < 0.001). Conversely, more than 4 h of daily TV, video, or computer use was positively associated with the likelihood of stroke (OR = 11.7, 95% CI = 2.1-219.2; P = 0.022).

conclusionDifferent types, frequencies, and intensities of physical activity were associated with reduced stroke incidence, implying that there is an option for everyone. Daily or every other day activities are more critical in reducing stroke than reducing sedentary behavior duration.

Indexed as

ExerciseStrokeCase-Control StudiesCross-Sectional StudiesHumansNutrition Surveys

Identifiers

PMID35094505
PMCPMC8935290

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.