Evidence map›Paper›PMID 35094296›Full record

ArticleProbiotics and antimicrobial proteins2022

Anticancer Properties of Probiotic Saccharomyces boulardii Supernatant on Human Breast Cancer Cells.

Babak Pakbin, Shaghayegh Pishkhan Dibazar, Samaneh Allahyari, Maryam Javadi, Zahra Amani, Alireza Farasat, Sina Darzi

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Article in Probiotics and antimicrobial proteins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 37 citations in OpenAlex.

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  12. Article
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  14. Potential probiotic and functional properties ofFrontiers in microbiology · 2024
    Article
  15. Anti-inflammatory effect ofApplied and environmental microbiology · 2023
    Article
  16. Article
  17. Effects of ProbioticInternational journal of molecular sciences · 2023
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Babak PakbinMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
Shaghayegh Pishkhan DibazarDepartment of Immunology, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran.
Samaneh AllahyariDepartment of Food Hygiene and Safety, School of Health, Qazvin University of Medical Sciences, Qazvin, Iran.
Maryam JavadiChildren Growth and Development Research Center, Research Institute for Prevention of Non- Communicable Disease, Qazvin University of Medical Sciences, P.O. Box: 34185-754, Bahonar Blvd., Qazvin, Iran. Mjavadi@qums.ac.ir.
Zahra AmaniMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
Alireza FarasatDepartment of Medical Biotechnology, Qazvin University of Medical Sciences, Qazvin, Iran.
Sina DarziHealth Products Safety Research Center, Qazvin University of Medical Science, Qazvin, Iran.
Qazvin University of Medical Sciences · IRTarbiat Modares University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Saccharomyces boulardii, a variety of S. cerevisiae, is used as a probiotic yeast in food and drug industries. However, S. boulardii is an opportunistic pathogen, and the supernatant of this organism has recently been recommended for its health-promoting benefits. Breast cancer is the most frequent cancer disease in women worldwide. The objective of this study was to investigate the effects of S. boulardii supernatant (SBS) on cell viability, inducing apoptosis and suppression of survivin gene expression in MCF-7 and MCF-7/MX as human non-drug-resistant and multidrug-resistant breast cancer cells respectively. The IC

Indexed as

Breast NeoplasmsProbioticsSaccharomyces boulardiiFemaleHumansProspective StudiesSaccharomyces cerevisiaeSurvivinSurvivinAnticancer propertiesBreast carcinomaIn vitro studyProbiotic Saccharomyces boulardiiYeast supernatant

Identifiers

PMID35094296
OpenAlexW4210601638

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.