Evidence map›Paper›PMID 35094225›Full record

ArticleInternational ophthalmology2022

Ocular surface squamous neoplasia in India: a study of 438 patients.

Swathi Kaliki, Vijitha S Vempuluru, Neha Ghose, Shruthi Gunda, Nidhi Mahendra Vithalani, Shahenaz Sultana, Anasua Ganguly, Kavya Madhuri Bejjanki, Saumya Jakati, Dilip K Mishra

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Article in International ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Enhanced Imaging of Ocular Surface Lesions.Journal of clinical medicine · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Swathi KalikiThe Operation Eyesight, Universal Institute for Eye Cancer, L V Prasad Eye Institute, Hyderabad, 500034, India. kalikiswathi@yahoo.com.ORCID http://orcid.org/0000-0002-0800-9961
Vijitha S VempuluruThe Operation Eyesight, Universal Institute for Eye Cancer, L V Prasad Eye Institute, Hyderabad, 500034, India.
Neha GhoseThe Operation Eyesight, Universal Institute for Eye Cancer, L V Prasad Eye Institute, Hyderabad, 500034, India.
Shruthi GundaThe Operation Eyesight, Universal Institute for Eye Cancer, L V Prasad Eye Institute, Hyderabad, 500034, India.
Nidhi Mahendra VithalaniThe Operation Eyesight, Universal Institute for Eye Cancer, L V Prasad Eye Institute, Hyderabad, 500034, India.
Shahenaz SultanaThe Operation Eyesight, Universal Institute for Eye Cancer, L V Prasad Eye Institute, Hyderabad, 500034, India.
Anasua GangulyThe Operation Eyesight, Universal Institute for Eye Cancer, L V Prasad Eye Institute, Hyderabad, 500034, India.
Kavya Madhuri BejjankiThe Operation Eyesight, Universal Institute for Eye Cancer, L V Prasad Eye Institute, Hyderabad, 500034, India.
Saumya JakatiOphthalmic Pathology Services, L V Prasad Eye Institute, Hyderabad, India.
Dilip K MishraOphthalmic Pathology Services, L V Prasad Eye Institute, Hyderabad, India.
L V Prasad Eye Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the clinical features, histopathology, treatment, and outcomes of patients with ocular surface squamous neoplasia (OSSN) presenting to a referral centre in India.

methodsRetrospective interventional study.

resultsOf 438 patients, the mean age at presentation was 49 years. Human immunodeficiency virus infection was noted in 72 (16%), xeroderma pigmentosum in 22 (5%), hepatitis B virus infection in 14 (3%), and systemic cancer in 8 (2%) patients. Tumor pigmentation was noted in 243 (54%) tumors with a mean percentage of tumor pigmentation of 44% (median, 40%; range, 1 to 100%). Intraocular tumor extension was noted in 12 (3%), and orbital tumor extension in 16 (4%) eyes. Of the 381 treated lesions, excisional biopsy (n = 247; 65%) was the most common treatment modality. Of the 311 lesions with histopathology diagnosis of OSSN, invasive squamous cell carcinoma (n = 92; 30%) was the most common. Over a mean follow-up period of 11 months (median, 5 months; range, 1 to 108 months) in 368 patients, tumor recurrence was noted in 16 (4%) eyes, globe salvage was achieved in 341 (90%) eyes, vision salvage in 338 (89%) eyes, regional lymph node metastasis occurred in 9 (2%), and metastasis-related death in 9 (2%) patients.

conclusionPigmented OSSN is common in Asian Indian population. Appropriate management of OSSN is associated with good vision, globe, and life salvage rates in India.

Indexed as

Carcinoma, Squamous CellConjunctival NeoplasmsEye NeoplasmsHumansIndiaNeoplasm Recurrence, LocalRetrospective StudiesConjunctivaEyeOcular surface squamous neoplasiaOSSNTumor

Identifiers

PMID35094225
OpenAlexW4210352694

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.