ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2022
The relationship between physical and mental health multimorbidity and children's health-related quality of life.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A systematic scoping review and gap analysis of questionnaires to assess multimorbidity among children.Pediatric research · 2026Pooled it
- The magnitude of multimorbidity in childhood: a global systematic review.Systematic reviews · 2026Pooled it
- Age differences in psychological comorbidity in atopic dermatitis: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Internal Consistency and Validity of a Short Spanish Version (10-Items) of the Center for Epidemiological Studies Depression Scale for Children and Adolescents (CES-DC).Depression and anxiety · 2024Trial
- Youth stress, happiness, and life satisfaction across morbidity status: a gender-stratified analysis.Scientific reports · 2026Article
- Physical and mental health professionals perspectives of providing mental health care for young people: A qualitative interview study.PLOS mental health · 2026Article
- Health-Related Quality of Life and Its Association With Multimorbidity Among University Students in Jeddah, Saudi Arabia: A Cross-Sectional Study.Journal of patient experience · 2026Article
- No association between joint hypermobility, musculoskeletal pain and neurodevelopmental problems in a school-based sample of 11-year-old children.BJPsych open · 2025Article
- Research priorities on physical-mental comorbidity in children and adolescents: an international consensus.EClinicalMedicine · 2025Review
- Healthy Lifestyle Matters: A Network Analysis of Urban Chinese Pre-School Children's Adiposity, Sleep Health, Mental Health, Child Functioning and Health Behaviours.Child: care, health and development · 2025Article
- A Scoping Review of Parenting Interventions with a Dual Focus on Improving Child Emotional and Physical Health.Research square · 2025Article
- Predicting children and adolescents at high risk of poor health‑related quality of life using machine learning methods.Health and quality of life outcomes · 2025Article
- Neonatal multimorbidity and the phenotype of premature aging in preterm infants.Pediatric research · 2025Review
- The relationship between household food insecurity and quality of life among children aged 7-13 years: effects of parent-reported disordered eating, anxiety and depression.BMC public health · 2025Article
- Patterns of symptom deterioration can support multimorbidity management in COPD: Perspectives of patients and healthcare professionals.PloS one · 2025Article
- Clustering of Dietary Patterns Associated with Health-Related Quality of Life in Spanish Children and Adolescents.Nutrients · 2024Article
- Comparing the Psychometric Performance of Generic Paediatric Health-Related Quality of Life Instruments in Children and Adolescents with ADHD, Anxiety and/or Depression.PharmacoEconomics · 2024Article
- From PHQ-2 to SRS-22: how a depression screening tool relates to SRS scores in patients with adolescent idiopathic scoliosis.Spine deformity · 2024Article
- The Father's Part: A Pilot Evaluation of a Father-Centered Family Intervention Group in Child and Adolescent Psychiatry.Behavioral sciences (Basel, Switzerland) · 2023Article
- The Father's Part: Influences of Paternal Psychopathology and Parenting Behavior on Child and Adolescent Well-Being.Healthcare (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
purposeTo examine the relationships between physical health problems, and borderline or clinical levels of mental health symptoms and children's health-related quality of life (HRQoL).
methodsData were from the Longitudinal Study of Australian Children (2004-2018). Parents reported on their child's HRQoL (PedsQL), physical health problems and mental health symptoms (Strengths and Difficulties Questionnaire, SDQ). A pooled cross-sectional analysis using linear regressions examined the relationships between physical health and clinical/borderline mental health symptoms, individually and when multi-morbid, and children's HRQoL, and whether these relationships vary by a range of child, family and social factors.
resultsThe sample comprised 47,567 observations of children aged 4-17 years. Borderline and clinical levels of mental health symptoms were associated with significantly lower HRQoL, equal to more than two-times (10.5 points) and more than three-times (16.8 points) the clinically meaningful difference, respectively. This was a larger difference than that associated with physical health problems (4.4 points). We found a significant interaction effect between physical health problems and clinical mental health symptoms which was associated with even poorer HRQoL after accounting for the individual relationships of both problems. Mental health problems were associated with poorer HRQoL for older versus younger children; and the interaction effect was significant for boys but not girls.
conclusionFindings highlight the importance of identifying and addressing mental health symptoms in children of all ages, even if these problems do not meet formal clinical criteria. Particular attention should be paid to the mental health and HRQoL of children with physical-mental multimorbidity, who are at risk of disproportionately poorer HRQoL.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.