Evidence map›Paper›PMID 35094143›Full record

ArticleActa diabetologica2022

Predictive value of admission glycemia in diabetics with pulmonary embolism compared to non-diabetic patients.

Ljiljana Jovanovic, Milena Rajkovic, Vesna Subota, Bojana Subotic, Boris Dzudovic, Jovan Matijasevic, Marija Benic, Sonja Salinger, Stefan Simovic, Vladimir Miloradovic and 8 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Acta diabetologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 3 countries.

Ljiljana JovanovicInstitute of Medical Biochemistry, Military Medical Academy, Belgrade, Serbia.
Milena RajkovicInstitute of Medical Biochemistry, Military Medical Academy, Belgrade, Serbia.
Vesna SubotaInstitute of Medical Biochemistry, Military Medical Academy, Belgrade, Serbia.
Bojana SuboticClinic of Cardiology and Emergency Internal Medicine, Military Medical Academy, School of Medicine, University of Defense, Belgrade, Serbia.
Boris DzudovicClinic of Cardiology and Emergency Internal Medicine, Military Medical Academy, School of Medicine, University of Defense, Belgrade, Serbia.
Jovan MatijasevicInstitute for Pulmonary Diseases of Vojvodina, Sremska Kamenica, Serbia.
Marija BenicInstitute for Pulmonary Diseases of Vojvodina, Sremska Kamenica, Serbia.
Sonja SalingerClinic of Cardiology, Clinical Center Nis, University of Nis, Nis, Serbia.
Stefan SimovicClinic of Cardiology, Clinical Center Kragujevac, School of Medicine, University of Kragujevac, Kragujevac, Serbia.
Vladimir MiloradovicClinic of Cardiology, Clinical Center Kragujevac, School of Medicine, University of Kragujevac, Kragujevac, Serbia.
Tamara Preradovic KovacevicClinic of Cardiology, Clinical Center Banja Luka, School of Medicine, University of Banja Luka, Banja Luka, Republic of Srpska, Bosnia and Herzegovina.
Ljiljana KosClinic of Cardiology, Clinical Center Banja Luka, School of Medicine, University of Banja Luka, Banja Luka, Republic of Srpska, Bosnia and Herzegovina.
Aleksandar NeskovicDepartment of Cardiology, Clinical Hospital Center Zemun, Belgrade, Serbia.
Srdjan KafedzicDepartment of Cardiology, Clinical Hospital Center Zemun, Belgrade, Serbia.
Natasa Markovic NikolicFaculty of Medicine, University of Belgrade, Belgrade, Serbia.
Bjanka BozovicClinic of Cardiology, Clinical Center Podgorica, School of Medicine, University of Podgorica, Podgorica, Montenegro.
Nebojsa BulatovicClinic of Cardiology, Clinical Center Podgorica, School of Medicine, University of Podgorica, Podgorica, Montenegro.
Slobodan ObradovicClinic of Cardiology and Emergency Internal Medicine, Military Medical Academy, School of Medicine, University of Defense, Belgrade, Serbia. sloba.d.obradovic@gmail.com.ORCID http://orcid.org/0000-0001-5711-5851
Military Medical Academy · RSUniversity of Banja Luka · BAUniversity of Belgrade · RSUniversity of Kragujevac · RSInstitute for Pulmonary Diseases of Vojvodina · RSUniversity of Defence · RSUniversity of Montenegro · MEUniversity of Nis · RSUniversity of Novi Sad · RSZemun Hospital · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo examine the relationship between admission glucose (AG) level and short-term in-hospital mortality and to investigate the association between hyperglycemia and major bleeding in PE patients with and without DMT2.

methodsWe evaluated 1165 patients with diagnosed acute PE with multi-detector computed tomography pulmonary angiography (MDCT-PA) enrolled in the Regional multicenter PE registry (REPER). The study population was classified to patients with diabetes mellitus type 2 (DMT2) and those without diabetes. According to quartiles of AG patients, both groups separately were categorized into four subgroups (DMT2 I: < 7.5 mmol/L; II: 7.5-10.0 mmol/L; III: 10.0-15.7 mmol/L; IV: > 15.7 mmol/L and (non-DMT2 I: < 5.5 mmol/L; II: 5.5-6.3 mmol/L; III: 6.3-7.9 mmol/L; IV: > 7.9 mmol/L).

resultsAll-cause mortality was higher in the DMT2 group (9.5% vs. 18.2%, p < 0.001), and PE-cause mortality was 6% for the patients without DMT2 and 12.4% for DMT2 patients (p = 0.02). The patients in the fourth AG quartiles in both groups, without DMT2 and with DMT2, had significantly higher all-cause and PE-cause in-hospital mortality compared with the first quartile. Rates of major bleeding were similar between the groups. On the multivariable analysis, after adjusting for age, gender and mortality risk, the adherence in the fourth AG quartile had an independent predictive value for all-cause death (HR 2.476, 95% CI 1.017-6.027) only in DM patients.

conclusionIn our cohort of patients with acute PE, diabetes was associated with increased rates for all-cause and PE-cause mortality.

Indexed as

Diabetes MellitusHyperglycemiaPulmonary EmbolismBlood GlucoseHospitalizationHospital MortalityHumansPrognosisBlood GlucoseAdmission glucoseDiabetesMajor bleedingMortalityPulmonary embolism

Identifiers

PMID35094143
OpenAlexW4210525420

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.