ArticleCerebral cortex (New York, N.Y. : 1991)2022
Distinct roles for the anterior temporal lobe and angular gyrus in the spatiotemporal cortical semantic network.
Article in Cerebral cortex (New York, N.Y. : 1991), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed.
- A neurocognitive interactive activation model of semantic priming in lexical decisions.Scientific reports · 2026Article
- Listening to a Consonant Chord Progression during Live Face-to-Face Gaze Enhances Neural Activity in Social Systems.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Spatiotemporal Dynamics in Prespeech Semantic Category Decoding: An Intracranial EEG Study.eNeuro · 2026Article
- Controlled Semantic Cognition: Precision Recordings Converge With in Silico Experiments to Reveal the Inner Workings of the Anterior Temporal Lobe Hub.Neurobiology of language (Cambridge, Mass.) · 2026Review
- Linear and nonlinear multidimensional functional connectivity methods reveal similar networks for semantic processing in EEG/MEG data.Frontiers in human neuroscience · 2025Article
- A comparative analysis of face and object perception in 2D laboratory and virtual reality settings: insights from induced oscillatory responses.Experimental brain research · 2024Article
- How the intrinsic functional connectivity patterns of the semantic network support semantic processing.Brain imaging and behavior · 2024Article
- Decoding Semantics from Dynamic Brain Activation Patterns: From Trials to Task in EEG/MEG Source Space.eNeuro · 2024Article
- Harmonic memory signals in the human cerebral cortex induced by semantic relatedness of words.NPJ science of learning · 2024Article
- An eye on semantics: a study on the influence of concreteness and predictability on early fixation durations.Language, cognition and neuroscience · 2024Article
- Neuroanatomical correlates of language impairment in non-fluent variant of primary progressive aphasia.Frontiers in human neuroscience · 2024Article
- Immediate neural impact and incomplete compensation after semantic hub disconnection.Nature communications · 2023Article
- Time-Lagged Multidimensional Pattern Connectivity (TL-MDPC): An EEG/MEG pattern transformation based functional connectivity metric.NeuroImage · 2023Article
- Task modulation of spatiotemporal dynamics in semantic brain networks: An EEG/MEG study.NeuroImage · 2022Article
- Altered electroencephalographic networks in developmental dyslexia after remedial training: a prospective case-control study.Neural regeneration research · 2021Article
- Overlapping connectivity patterns during semantic processing of abstract and concrete words revealed with multivariate Granger Causality analysis.Scientific reports · 2020Article
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4 authors.
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Abstract
Semantic knowledge is supported by numerous brain regions, but the spatiotemporal configuration of the network that links these areas remains an open question. The hub-and-spokes model posits that a central semantic hub coordinates this network. In this study, we explored distinct aspects that define a semantic hub, as reflected in the spatiotemporal modulation of neural activity and connectivity by semantic variables, from the earliest stages of semantic processing. We used source-reconstructed electro/magnetoencephalography, and investigated the concreteness contrast across three tasks. In a whole-cortex analysis, the left anterior temporal lobe (ATL) was the only area that showed modulation of evoked brain activity from 100 ms post-stimulus. Furthermore, using Dynamic Causal Modeling of the evoked responses, we investigated effective connectivity amongst the candidate semantic hub regions, that is, left ATL, supramarginal/angular gyrus (SMG/AG), middle temporal gyrus, and inferior frontal gyrus. We found that models with a single semantic hub showed the highest Bayesian evidence, and the hub region was found to change from ATL (within 250 ms) to SMG/AG (within 450 ms) over time. Our results support a single semantic hub view, with ATL showing sustained modulation of neural activity by semantics, and both ATL and AG underlying connectivity depending on the stage of semantic processing.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.