Evidence map›Paper›PMID 35093132›Full record

ArticleJournal of orthopaedic surgery and research2022

The validity and accuracy of 3D-printed patient-specific instruments for high tibial osteotomy: a cadaveric study.

Zhuang Miao, Songlin Li, Desu Luo, Qunshan Lu, Peilai Liu

2 registry-linked trialsAbstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05448742 naunknown statusnot on this map

Novel, Biplanar, Medial Opening Wedge, Posterior Tibial Slope-reducing High Tibial Osteotomy Aided by Patient-specific Instruments, With Tibial Tuberosity Serving as Hinge Axis: Cadaveric Study Assessing Accuracy of Biplanar Correction With Various Coronal and Sagittal Amounts of Correction

TypeinterventionalSponsorArtromedical Konrad Malinowski ClinicRan2022 to 2022Enrolled6ConditionsKnee Disease, Knee Osteoarthritis, Knee Injuries and DisordersArmsBiplanar PSI slope-reducing MOWHTO.
NCT07212777 narecruitingnot on this mapstarted 2025, after this paper: background citation

Precisión de la osteotomía Tibial Proximal Con Instrumental Paciente-específico vs técnica Convencional

TypeinterventionalSponsorUniversity of MalagaRan2025 to 2028Enrolled50ConditionsArthritis (Knee), Varus KneeArmsMedial Open Wedge Hight Tibial Osteotomy using patient-specific instrumentation, Medial Open Wedge Hight Tibial Osteotomy using conventional surgery techniques
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Accuracy of medial opening wedge high tibial osteotomy using patient-specific instrumentation: a randomised cadaveric study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. [Application status of open-wedge high tibial osteotomy assisted by three-dimensional printing patient-specific cutting guides].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhuang MiaoDepartment of Orthopedics, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Songlin LiDepartment of Orthopedics, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Desu LuoDepartment of Orthopedics, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Qunshan LuDepartment of Orthopedics, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Peilai LiuDepartment of Orthopedics, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China. 199362000205@email.sdu.edu.cn.ORCID http://orcid.org/0000-0002-2661-8496

Funding

Clinical Application-oriented Medical Innovation Foundation from National Clinical Research Center for Orthopedics, Sports Medicine & Rehabilitation and Jiangsu China-Israel Industrial Technical Research Institute Foundation 2021-NCRC-CXJJ-PY-14Horizontal project of Shandong University 6010120015
6 · The paper itself

Abstract

objectiveHigh tibial osteotomy (HTO) has been used for the treatment of patients with knee osteoarthritis. However, the successful implementation of HTO requires precise intraoperative positioning, which places greater requirements on the surgeon. In this study, we aimed to design a new kind of 3D-printed patient-specific instrument (PSI) for HTO, including a positioning device and an angle bracing spacer, and verify its effectiveness using cadaveric specimens.

methodsThis study included ten fresh human lower-limb cadaveric specimens. Computed tomography (CT) and X-ray examinations were performed to make preoperative plans. PSI was designed and 3D-printed according to the preoperative plan. Then, the PSI was used to guide HTO. Finally, we performed X-ray and CT after the operation to verify its validity and accuracy.

resultsThe PSI using process was adjusted according to the pre-experimental procedure in 1 case. Hinge fracture occurred in 1 case. According to X-rays of the remaining eight cadaveric specimens, no statistically significant difference was noted between the preoperative planning medial proximal tibial angle (MPTA) and postoperative MPTA (P > 0.05) or the preoperative and postoperative posterior slope angle (PSA) (P > 0.05). According to the CT of 10 cadaveric specimens, no statistically significant difference was noted between the design angle and actual angle, which was measured according to the angle between the osteotomized line and the cross section (P > 0.05). The gap between the designed osteotomy line and the actual osteotomy line was 2.09 (0.8 ~ 3.44) mm in the coronal plane and 1.58 (0.7 ~ 2.85) mm in the sagittal plane.

conclusionThis 3D-printed PSI of HTO accurately achieves the angle and position of the preoperative plan without increasing the stripping area. However, its use still requires a certain degree of proficiency to avoid complications, such as hinge fracture.

Indexed as

Osteoarthritis, KneeOsteotomyPrinting, Three-DimensionalCadaverFractures, BoneHumansKnee JointRadiographyReproducibility of ResultsTibiaTomography, X-Ray Computed3D-printedAccuracyCadaveric studyHigh tibial osteotomyPatient-specific instrumentValidity

Identifiers

PMID35093132
PMCPMC8800288

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.