Evidence map›Paper›PMID 35093012›Full record

ArticleBMC infectious diseases2022

Preventing COVID-19 outbreaks through surveillance testing in healthcare facilities: a modelling study.

Tim Litwin, Jens Timmer, Mathias Berger, Andreas Wahl-Kordon, Matthias J Müller, Clemens Kreutz

Abstract read
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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  7. Utility of routine post-admission testing for SARS-CoV-2 in a rehabilitation facility.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024
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  11. Article
  12. A robust, highly multiplexed mass spectrometry assay to identify SARS-CoV-2 variants.medRxiv : the preprint server for health sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tim LitwinInstitute of Medical Biometry and Statistics (IMBI), Faculty of Medicine and Medical Center, University of Freiburg, 79104, Freiburg, Germany. litwin@imbi.uni-freiburg.de.ORCID http://orcid.org/0000-0001-6851-8656
Jens TimmerFreiburg Center for Data Analysis and Modelling (FDM), University of Freiburg, 79104, Freiburg, Germany.ORCID http://orcid.org/0000-0003-4517-1383
Mathias BergerDepartment of Psychiatry and Psychotherapy, Medical Center, Faculty of Medicine, University of Freiburg, 79104, Freiburg, Germany.
Andreas Wahl-KordonOberberg Hospital Schwarzwald, 78132, Hornberg, Germany.ORCID http://orcid.org/0000-0002-1045-1994
Matthias J MüllerOberberg Group, 10117, Berlin, Germany.ORCID http://orcid.org/0000-0002-7577-2748
Clemens KreutzInstitute of Medical Biometry and Statistics (IMBI), Faculty of Medicine and Medical Center, University of Freiburg, 79104, Freiburg, Germany.ORCID http://orcid.org/0000-0002-8796-5766

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurveillance testing within healthcare facilities provides an opportunity to prevent severe outbreaks of coronavirus disease 2019 (COVID-19). However, the quantitative impact of different available surveillance strategies and their potential to decrease the frequency of outbreaks are not well-understood.

methodsWe establish an individual-based model representative of a mental health hospital yielding generalizable results. Attributes and features of this facility were derived from a prototypical hospital, which provides psychiatric, psychosomatic and psychotherapeutic treatment. We estimate the relative reduction of outbreak probability for three test strategies (entry test, once-weekly test and twice-weekly test) relative to a symptom-based baseline strategy. Based on our findings, we propose determinants of successful surveillance measures.

resultsEntry Testing reduced the outbreak probability by 26%, additionally testing once or twice weekly reduced the outbreak probability by 49% or 67% respectively. We found that fast diagnostic test results and adequate compliance of the clinic population are mandatory for conducting effective surveillance. The robustness of these results towards uncertainties is demonstrated via comprehensive sensitivity analyses.

conclusionsWe conclude that active testing in mental health hospitals and similar facilities considerably reduces the number of COVID-19 outbreaks compared to symptom-based surveillance only.

Indexed as

COVID-19Delivery of Health CareDisease OutbreaksHealth FacilitiesHumansSARS-CoV-2Agent-based modelCOVID-19Infectious disease surveillanceLong-term carePoint-of-care testing

Identifiers

PMID35093012
PMCPMC8800405

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.