Evidence map›Paper›PMID 35093002›Full record

Observational studyBMC pregnancy and childbirth2022

Tamil Nadu Pregnancy and Heart Disease Registry (TNPHDR): design and methodology.

Justin Paul Gnanaraj, S Anne Princy, Karen Sliwa-Hahnle, Sowmya Sathyendra, Nambirajan Jeyabalan, Ragothaman Sethumadhavan, Selvarani G, N Sumathi, Vinotha S, Pachaiappan P and 10 more

Open access · goldAbstract readClinical Trial ProtocolMulticenter StudyObservational Study
In one paragraph

Observational study in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 8 institutions in 1 country.

Justin Paul GnanarajMadras Medical College and Research Institute, Chennai, India. drjpheart@gmail.com.
S Anne PrincyTamil Nadu Government Multi Super Speciality Hospital, Chennai, India.
Karen Sliwa-HahnleHatter Institute for Cardiovascular Research in Africa, Cape Town, South Africa.
Sowmya SathyendraChristian Medical College, Vellore, India.
Nambirajan JeyabalanCoimbatore Medical College, Coimbatore, India.
Ragothaman SethumadhavanGovernment Medical College, Chengalpattu, India.
Selvarani GGovernment Medical College, Madurai, India.
N SumathiGovernment Medical College, Madurai, India.
Vinotha SGovernment KAPV Medical College, Tiruchirappalli, India.
Pachaiappan PGovernment MKM Medical College, Salem, India.
Vimali MuraliMadras Medical College and Research Institute, Chennai, India.
Shanthirani BGovernment Medical College, Theni, India.
Gomathi TGovernment Medical College, Tanjore, India.
Muthuprabha PTirunelveli Medical College, Tirunelveli, India.
Panniyammakal JeemonSree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.
E ElavarasiMadras Medical College and Research Institute, Chennai, India.
Rajarajeshwari RGovernment Medical College, Tanjore, India.
Vijaya SMadras Medical College and Research Institute, Chennai, India.
Kanmani KMadras Medical College and Research Institute, Chennai, India.
TNPHDR investigators
Madras Medical College · INGovernment Medical College · INMadurai Medical College · INChristian Medical College & Hospital · INCoimbatore Medical College and Hospital · INSree Chitra Thirunal Institute for Medical Sciences and Technology · INTamil Nadu Government Multi Super Speciality Hospital · INTirunelveli Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac disease in pregnancy is a major contributor to maternal mortality in high, middle and low-income countries. Availability of data on outcomes of pregnancy in women with heart disease is important for planning resources to reduce maternal mortality. Prospective data on outcomes and risk predictors of mortality in pregnant women with heart disease (PWWHD) from low- and middle-income countries are scarce.

methodsThe Tamil Nadu Pregnancy and Heart Disease Registry (TNPHDR) is a prospective, multicentric and multidisciplinary registry of PWWHD from 29 participating sites including both public and private sectors, across the state of Tamil Nadu in India. The TNPHDR is aimed to provide data on incidence of maternal and fetal outcomes, adverse outcome predictors, applicability of the modified World Health Organization (mWHO) classification of maternal cardiovascular risk and the International risk scoring systems (ZAHARA and CARPREG I & II) in Indian population and identify possible gaps in the existing management of PWWHD. Pregnancy and heart teams will be formed in all participating sites. Baseline demographic, clinical, laboratory and imaging parameters, data on counselling received, antenatal triage and management, peripartum management and postpartum care will be collected from 2500 eligible participants as part of the TNPHDR. Participants will be followed up at one, three and six-months after delivery/termination of pregnancy to document study outcomes. Predictors of maternal and foetal outcome will be identified. DISCUSSION: The TNPHDR will be the first representative registry from low- and middle-income countries aimed at providing crucial information on pregnancy outcomes and risk predictors in PWWHD. The results of TNPHDR could help to formulate steps for improved care and to generate a customised and practical guideline for managing pregnancy in women with heart disease in limited resource settings.

trial registrationThe TNPHDR is registered under Clinical Trials Registry-India ( CTRI/2020/01/022736 ).

Indexed as

RegistriesFemaleHeart DiseasesHumansIndiaMaternal MortalityPregnancyPregnancy Complications, CardiovascularPregnancy OutcomeRisk FactorsHeart diseaseMaternal outcomeMortalityPregnancyRisk prediction

Identifiers

PMID35093002
PMCPMC8801092
OpenAlexW4210439235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.