Evidence map›Paper›PMID 35092924›Full record

ArticleBiosensors & bioelectronics2022

ACE2-based capacitance sensor for rapid native SARS-CoV-2 detection in biological fluids and its correlation with real-time PCR.

A Georgas, E Lampas, D P Houhoula, A Skoufias, S Patsilinakos, I Tsafaridis, G P Patrinos, N Adamopoulos, A Ferraro, E Hristoforou

Open access · greenAbstract read
In one paragraph

Article in Biosensors & bioelectronics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  8. Capacitive immunosensor for COVID-19 diagnosis.Microelectronic engineering · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

A GeorgasNational Technical University of Athens, Zografou Campus 9, Iroon Polytechniou str Zografou, 15780, Greece. Electronic address: antonisgeo@mail.ntua.gr.
E LampasKonstantopoulio General Hospital, Agias Olgas 3-5, Nea Ionia, 142 33, Greece.
D P HouhoulaUniversity of West Attica, Agiou Spyridonos 28, Egaleo, 122 43, Greece.
A SkoufiasNational Technical University of Athens, Zografou Campus 9, Iroon Polytechniou str Zografou, 15780, Greece.
S PatsilinakosKonstantopoulio General Hospital, Agias Olgas 3-5, Nea Ionia, 142 33, Greece.
I TsafaridisKatharsis Technologies Inc., 1200-1075, West Georgia Street, Vancouver, BC, Canada.
G P PatrinosUniversity of Patras, University Campus, 26504, Rio, Greece.
N AdamopoulosGalenica SA, Eleftherias 4, Kifisia, 145 64, Greece.
A FerraroNational Technical University of Athens, Zografou Campus 9, Iroon Polytechniou str Zografou, 15780, Greece.
E HristoforouNational Technical University of Athens, Zografou Campus 9, Iroon Polytechniou str Zografou, 15780, Greece.
National Technical University of Athens · GRAgia Olga Hospital · GRAXYS Technologies (Canada) · CAUniversity of Patras · GRUniversity of West Attica · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spread of the SARS-CoV-2 and its increasing threat to human health worldwide have necessitated the development of new technological tools to combat the virus. Particular emphasis is given to the development of diagnostic methods that monitor the spread of the virus rapidly and effectively. In this study, we report the development and testing of an antibody-free biosensor, based on the immobilization of ACE2 protein on the surface of gold interdigitated electrode. When the sensor was used in laboratory conditions for targeting the virus' structural spike protein, it showed a limit of detection [LOD] of 750 pg/μL/mm

Indexed as

Biosensing TechniquesCOVID-19Angiotensin-Converting Enzyme 2HumansReal-Time Polymerase Chain ReactionReproducibility of ResultsSARS-CoV-2Angiotensin-Converting Enzyme 2Antibody freeDetectionInterdigitated electrodesSARS-CoV-2 biosensor

Identifiers

PMID35092924
PMCPMC8776344
OpenAlexW4206012550

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.