Evidence map›Paper›PMID 35092567›Full record

ReviewProbiotics and antimicrobial proteins2023

Bacillus Species as Direct-Fed Microbial Antibiotic Alternatives for Monogastric Production.

Shifa A Bahaddad, Meshal H K Almalki, Othman A Alghamdi, Sayed S Sohrab, Muhammad Yasir, Esam I Azhar, Hichem Chouayekh

Abstract readReview
In one paragraph

Review in Probiotics and antimicrobial proteins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Review
  6. Detoxification of Ochratoxin A byFoods (Basel, Switzerland) · 2026
    Article
  7. Article
  8. Coencapsulation of MultistrainInternational journal of microbiology · 2026
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Effect ofAnimals : an open access journal from MDPI · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shifa A BahaddadDepartment of Biological Sciences, College of Science, University of Jeddah, Jeddah, Kingdom of Saudi Arabia.
Meshal H K AlmalkiDepartment of Biological Sciences, College of Science, University of Jeddah, Jeddah, Kingdom of Saudi Arabia.
Othman A AlghamdiDepartment of Biological Sciences, College of Science, University of Jeddah, Jeddah, Kingdom of Saudi Arabia.
Sayed S SohrabSpecial Infectious Agents Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Muhammad YasirSpecial Infectious Agents Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Esam I AzharSpecial Infectious Agents Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Hichem ChouayekhDepartment of Biological Sciences, College of Science, University of Jeddah, Jeddah, Kingdom of Saudi Arabia. hschouayekh@uj.edu.sa.ORCID 0000-0003-3894-1116

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic growth promoters have been utilized for long time at subtherapeutic levels as feed supplements in monogastric animal rations. Because of their side-effects such as antibiotic resistance, reduction of beneficial bacteria in the gut, and dysbiosis, it is necessary to look for non-therapeutic alternatives. Probiotics play an important role as the key substitutes to antibacterial agents due to their many beneficial effects on the monogastric animal host. For instance, enhancement of the gut microbiota balance can contribute to improvement of feed utilization efficiency, nutrients absorption, growth rate, and economic profitability of livestock. Probiotics are defined as "live microorganisms that, when administered in adequate amounts, confer a health benefit on the host." They are available in diverse forms for use as feed supplements. Their utilization as feed additives assists in good digestion of feed ingredients and hence, making the nutrients available for promoting growth. Immunity can also be enhanced by supplementing probiotics to monogastrics diets. Moreover, probiotics can help in improving major meat quality traits and countering a variety of monogastric animals infectious diseases. A proper selection of the probiotic strains is required in order to confer optimal beneficial effects. The present review focuses on the general functional, safety, and technological screening criteria for selection of ideal Bacillus probiotics as feed supplements as well as their mechanism of action and beneficial effects on monogastric animals for improving production performance and health status.

Indexed as

BacillusProbioticsAnimal FeedAnimalsAnti-Bacterial AgentsDietDietary SupplementsAnti-Bacterial AgentsAntibiotic alternativeBacillusFeed additiveGut microbiotaMode of actionProbiotic

Identifiers

PMID35092567
PMCPMC8799964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.