Evidence map›Paper›PMID 35092497›Full record

ReviewCell and tissue research2023

Prion disease modelled in Drosophila.

Raymond Bujdoso, Andrew Smith, Oliver Fleck, John Spiropoulos, Olivier Andréoletti, Alana M Thackray

Open access · hybridAbstract readReview
In one paragraph

Review in Cell and tissue research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. New developments in prion disease research.Cell and tissue research · 2023
    Article
  4. Intrinsic determinants of prion protein neurotoxicity inFrontiers in molecular neuroscience · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Raymond BujdosoDepartment of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, CB3 OES, UK. rb202@cam.ac.uk.ORCID http://orcid.org/0000-0002-5068-3247
Andrew SmithDepartment of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, CB3 OES, UK.
Oliver FleckDepartment of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, CB3 OES, UK.
John SpiropoulosPathology Department, Animal and Plant Health Agency (APHA), Weybridge, Woodham Lane, New Haw, Surrey, KT15 3NB, Addlestone, UK.
Olivier AndréolettiUMR INRA ENVT 1225-Hôtes-Agents Pathogènes, Ecole Nationale Vétérinaire de Toulouse, 23 Chemin des Capelles, 31076, Toulouse, France.
Alana M ThackrayDepartment of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, CB3 OES, UK. amt27@cam.ac.uk.
University of Cambridge · GBAnimal and Plant Health Agency · GBBangor University · GBÉcole Nationale Vétérinaire de Toulouse · FR

Funding

National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/K000462/1National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/R00093X/1
6 · The paper itself

Abstract

Prion diseases are fatal neurodegenerative conditions of humans and various vertebrate species that are transmissible between individuals of the same or different species. A novel infectious moiety referred to as a prion is considered responsible for transmission of these conditions. Prion replication is believed to be the cause of the neurotoxicity that arises during prion disease pathogenesis. The prion hypothesis predicts that the transmissible prion agent consists of PrP

Indexed as

Prion DiseasesPrionsAnimalsAnimals, Genetically ModifiedDrosophilaDrosophila melanogasterHumansMammalsPrionsDrosophilaInfectivityNeurodegenerationPrionTransmissible

Identifiers

PMID35092497
PMCPMC10113284
OpenAlexW4221029523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.