Evidence map›Paper›PMID 35092454›Full record

ArticleApplied microbiology and biotechnology2022

Autotrophic lactate production from H

Alexander Mook, Matthias H Beck, Jonathan P Baker, Nigel P Minton, Peter Dürre, Frank R Bengelsdorf

Open access · hybridAbstract read
In one paragraph

Article in Applied microbiology and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Synthetic autotrophic yeast enables high itaconic acid production from COGreen chemistry : an international journal and green chemistry resource : GC · 2025
    Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Recombinant Production ofMicroorganisms · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. A fluorescent reporter system for anaerobic thermophiles.Frontiers in bioengineering and biotechnology · 2023
    Article
  20. Novel synthetic co-culture ofEngineering in life sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Alexander MookInstitute of Microbiology and Biotechnology, University of Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Germany.ORCID http://orcid.org/0000-0003-0834-3780
Matthias H BeckInstitute of Microbiology and Biotechnology, University of Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Germany.ORCID http://orcid.org/0000-0003-1793-0629
Jonathan P BakerClostridia Research Group, BBSRC/EPSRC Synthetic Biology Research Centre (SBRC), University of Nottingham, Nottingham, UK.
Nigel P MintonClostridia Research Group, BBSRC/EPSRC Synthetic Biology Research Centre (SBRC), University of Nottingham, Nottingham, UK.ORCID http://orcid.org/0000-0002-9277-1261
Peter DürreInstitute of Microbiology and Biotechnology, University of Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Germany.ORCID http://orcid.org/0000-0002-5586-221X
Frank R BengelsdorfInstitute of Microbiology and Biotechnology, University of Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Germany. frank.bengelsdorf@uni-ulm.de.ORCID http://orcid.org/0000-0003-3802-9485
Universität Ulm · DEEngineering and Physical Sciences Research Council · GB

Funding

Deutsche Forschungsgemeinschaft 427864786ERA-IB5 031A566A
6 · The paper itself

Abstract

Lactate has various uses as industrial platform chemical, poly-lactic acid precursor or feedstock for anaerobic co-cultivations. The aim of this study was to construct and characterise Acetobacterium woodii strains capable of autotrophic lactate production. Therefore, the lctBCD genes, encoding the native Lct dehydrogenase complex, responsible for lactate consumption, were knocked out. Subsequently, a gene encoding a D-lactate dehydrogenase (LDHD) originating from Leuconostoc mesenteroides was expressed in A. woodii, either under the control of the anhydrotetracycline-inducible promoter P

Indexed as

Carbon DioxideLactic AcidAcetatesAcetobacteriumFluorescenceAcetatesCarbon DioxideLactic AcidAcetobacterium woodiiFASTFluorescent tagGas fermentationH2 + CO2Lactate dehydrogenase

Identifiers

PMID35092454
PMCPMC8882112
OpenAlexW4210289809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.