ArticlePediatric pulmonology2022
Relationship between lung function and exhaled volatile organic compounds in healthy infants.
Article in Pediatric pulmonology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 14 citations in OpenAlex.
- Residential Proximity Land Use Characteristics and Exhaled Volatile Organic Compounds' Impact on Pulmonary Function in Asthmatic Children.Journal of xenobiotics · 2025Article
- Impact of environmental exposures on exhaled breath and lung function: NELA Birth Cohort.ERJ open research · 2025Article
- Exposure to Crude Oil-Related Volatile Organic Compounds Associated with Lung Function Decline in a Longitudinal Panel of Children.International journal of environmental research and public health · 2022Article
- Relationship between lung function and exhaled volatile organic compounds in healthy infants.Pediatric pulmonology · 2022Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study is to assess, for the first time, the relationship between the volatilome and lung function in healthy infants, which may be of help for the early detection of certain respiratory diseases. Lung function tests are crucial in chronic respiratory diseases diagnosis. Moreover, volatile organic compounds (VOCs) analysis in exhaled breath is a noninvasive technique that enables the monitorization of oxidative stress, typical of some forms of airway inflammation.
methodsLung function was studied in 50 healthy infants of 3-8 months of age and the following parameters were obtained: forced vital capacity (FVC), forced expiratory volume at 0.5 s (FEV
resultsA negatively significant relationship has been observed between levels of acetone, tetradecane, and pentadecane in exhaled breath and several of the lung function parameters. Levels of acetone (feature m/z = 58) were significantly negatively associated with FVC and FVE
conclusionThe findings of this study highlight a significant association between VOCs related to oxidative stress and lung function in healthy infants.
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Registered trials
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